Results 51 to 60 of about 3,394,183 (296)

Excess mortality during the warm summer of 2015 in Switzerland.

open access: yesSwiss medical weekly, 2016
QUESTION UNDER STUDY In Switzerland, summer 2015 was the second warmest summer for 150 years (after summer 2003). For summer 2003, a 6.9% excess mortality was estimated for Switzerland, which corresponded to 975 extra deaths.
A. Vicedo-Cabrera   +3 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Muslim and Buddhist Youths in Switzerland: Individualising Religion and Striving for Recognition?

open access: yesSocial Inclusion, 2020
Since the second half of the 20th century, immigrants and refugees from numerous countries have arrived in Switzerland. With their long-term settlement, the immigrant minorities have established cultural and religious associations to maintain their ...
Martin Baumann   +1 more
doaj   +1 more source

Natural hazard fatalities in Switzerland from 1946 to 2015

open access: yes, 2016
. A database of fatalities caused by natural hazard processes in Switzerland was compiled for the period between 1946 and 2015. Using information from the Swiss flood and landslide damage database and the Swiss destructive avalanche database, the data ...
A. Badoux   +3 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Business Power in Noisy Politics: An Exploration Based on Discourse Network Analysis and Survey Data

open access: yesPolitics and Governance, 2020
This study links voter-centred and interest group perspectives to assess the role structurally powerful businesses can play in contested political issues.
Adrian Rinscheid
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

From the Periphery to the International Scene. Artistic Trajectories in the Trial of Mobility

open access: yesSwiss Journal of Sociology, 2017
Geographical mobility has become a norm of contemporary art. This article examines the spatial dynamics of artists as they face the challenges presented by peripheral territory in visual arts, putting their mobility and flexibility to the test.
Moroni Isabelle
doaj   +1 more source

From ‘total’ to ‘comprehensive’ national defence: the development of the concept in Europe

open access: yesJournal on Baltic Security, 2020
The article discusses the idea of comprehensive national defence from a wide historical and geographical perspective. Countries facing different security challenges have used the concept of involving the entire society in state defence. From a historical
Berzina Ieva
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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