Results 61 to 70 of about 6,561,632 (351)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Real-Time Discrimination of Symmetrical Faults from Power Swings [PDF]
Iranian Journal of Electrical and Electronic Engineering, 2023 For reliable operation, distance relays have to be blocked in case of stable power swings (SPSs). Because these relays are prone to detect an SPS as a symmetrical 3-phase fault according to their symmetric nature.
H. Yaghobi
doaj
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Simulation and experimental study of power flow in a seven‐phase transformer under fault conditions
IET Generation, Transmission & Distribution, 2022 Fault analysis is necessary to design a protection system and circuit breakers for a power system network. The multiphase system is a new technology so very little work is found for the fault analysis of a multiphase system contrary, unlike a three‐phase
Mohamed Aslam Husain +4 more
doaj +1 more source
Quantum integrable system with two color components in two dimensions
, 2001 The Davey-Stewartson 1(DS1) system[9] is an integrable model in two dimensions. A quantum DS1 system with 2 colour-components in two dimensions has been formulated.
A. Davey +19 more
core +1 more source
Point Process Algorithm: A New Bayesian Approach for Planet Signal Extraction with the Terrestrial Planet Finder [PDF]
, 2006 The capability of the Terrestrial Planet Finder Interferometer (TPF-I) for planetary signal extraction, including both detection and spectral characterization, can be optimized by taking proper account of instrumental characteristics and astrophysical ...
Brent Ware +7 more
core +2 more sources
Three/Four-leg Inverter Current Control Based on Generalized Symmetrical Components
Compel, 2018 Considering a scenario of high penetration of voltage source inverters in distribution grids, on which the number of conductors is variable, this paper proposes a current control approach for three- or four-leg inverters based on the generalized ...
E. Liberado +5 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source