Results 61 to 70 of about 9,122 (283)

The place of modern α-2-agonists in the intraoperative sedation of trauma / orthopedic patients

Perioperative Medicine, 2020
Modern traumatological operations have a number of features: duration, a large pool of age-related patients with low functional reserves, forced position of the body, operations are often under regional anesthesia with a conserved consciousness, which ...
A Domoratskiy, V Kryliuk, I Kuchynska, T Pylypenko, A Pavlenko, D Horban   +5 more
doaj   +1 more source

Sympatholytic Effects of Diethylaminoethanol in Man.

Experimental Biology and Medicine, 1949
Summary and ConclusionsDoses of diethyl-aminoethanol sufficient to produce high blood concentrations resulted in a temporary inhibition of sympathetic vasoconstrictor reflexes in man. It is suggested that the effects of the drug on arterial pressure and ventricular tachycardias are secondary to its sympatholytic action.
E D, FREIS, J R, STANTON, F C, MOISTER
openaire   +2 more sources

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

A Possible Case of Neurogenic Pulmonary Edema in a Sheep following Intracranial Surgery [PDF]

, 2016
A 3-year-old female crossbred sheep weighing 64 kg was anaesthetized for intracranial surgery as a part of a research project. Premedication and induction of anesthesia were uneventful as well as tracheal intubation.
Adami, C, Casoni, D, Giovannini, A E J, Precht, C M   +3 more
core   +2 more sources

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio, Cianci, Rosario, Coppolino, Giuseppe, Di Mario, Francesca, Farrah, Tariq E., Fuiano, Giorgio, Gigante, Antonietta, Rivoli, Laura, Rosato, Edoardo   +8 more
core   +1 more source

Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise. [PDF]

, 2015
Limb tissue and systemic blood flow increases with heat stress, but the underlying mechanisms remain poorly understood. Here, we tested the hypothesis that heat stress-induced increases in limb tissue perfusion are primarily mediated by local temperature-
Ali, L, Banker, DS, Chiesa, ST, González-Alonso, J, Kalsi, KK, Lotlikar, MD, Rakobowchuk, M, Trangmar, SJ   +7 more
core   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

European Journal of Heart Failure, EarlyView.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin, Johann Bauersachs, Magdy Abdelhamid, Suleman Aktaa, Hussam Al Ghorani, Antonio Bayes‐Genis, Jan Biegus, Michael Böhm, Javed Butler, Nicolas Girerd, Marco Metra, Wilfried Mullens, Hadi Skouri, Muthiah Vaduganathan, Seif El Hadidi, Giuseppe M.C. Rosano, Gianluigi Savarese   +16 more
wiley   +1 more source

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico, Stefano Turi, Marco Manazza, Giuliana Lo Bianco, Giacomo Monti, Alberto Zangrillo, Giovanni Landoni, Luigi Beretta   +7 more
wiley   +1 more source

Acute Metabolic Effects of Thiopental Anesthesia on Fed and Fasted Rats Chronically Treated With Bromocriptine

Journal of Pharmacological Sciences, 2003
We investigated the acute effects of thiopental anesthesia (4 mg/100 g, i.v.) on plasma glucose, insulin, triacylglycerol, and prolactin levels in rats treated with bromocriptine (BR) (0.4 mg/100 g body wt, i.p., for two weeks).
Antônio Ribeiro de Oliveira, Jr., Leida Maria Botion, Rachel Menezes Guerra, Rodrigo Bastos Fóscolo, Lucas José Campos Machado, Umeko Marubayashi, Adelina Martha dos Reis, Câ;ndido Celso Coimbra   +7 more
doaj   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source