Results 41 to 50 of about 6,053 (224)

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise. [PDF]

, 2015
Limb tissue and systemic blood flow increases with heat stress, but the underlying mechanisms remain poorly understood. Here, we tested the hypothesis that heat stress-induced increases in limb tissue perfusion are primarily mediated by local temperature-
Ali, L, Banker, DS, Chiesa, ST, González-Alonso, J, Kalsi, KK, Lotlikar, MD, Rakobowchuk, M, Trangmar, SJ   +7 more
core   +1 more source

Prophylactic Dexmedetomidine Reduces Junctional Ectopic Tachycardia and Facilitates Postoperative Recovery in Pediatric Cardiac Surgery: A Systematic Review and Meta‐Analysis of Prospective Trials

Pediatric Anesthesia, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of prophylactic dexmedetomidine in preventing Junctional Ectopic Tachycardia (JET) and its impact on postoperative recovery in pediatric congenital heart surgery, restricting analysis to prospective trials. Methods We systematically searched PubMed, Scopus, and CENTRAL through October 16, 2025, for
Michelle Singh, Arjun Anilkumar, Rohit Vondivillu Srinivasan, Jasim Abdul Jabbar, Naghul Malaichamy, Rethin Jayaraman   +5 more
wiley   +1 more source

Acute Metabolic Effects of Thiopental Anesthesia on Fed and Fasted Rats Chronically Treated With Bromocriptine

Journal of Pharmacological Sciences, 2003
We investigated the acute effects of thiopental anesthesia (4 mg/100 g, i.v.) on plasma glucose, insulin, triacylglycerol, and prolactin levels in rats treated with bromocriptine (BR) (0.4 mg/100 g body wt, i.p., for two weeks).
Antônio Ribeiro de Oliveira, Jr., Leida Maria Botion, Rachel Menezes Guerra, Rodrigo Bastos Fóscolo, Lucas José Campos Machado, Umeko Marubayashi, Adelina Martha dos Reis, Câ;ndido Celso Coimbra   +7 more
doaj   +1 more source

Thoracic Epidural Anesthesia Can Be Effective for the Short‐Term Management of Ventricular Tachycardia Storm [PDF]

, 2017
Background Novel therapies aimed at modulating the autonomic nervous system, including thoracic epidural anesthesia (TEA), have been shown in small case series to be beneficial in treating medically refractory ventricular tachycardia (VT) storm. However,
Ajijola Olujimi A., Boyle Noel G., Bradfield Jason, Do Duc H., Le John, Mahajan Aman, Nogami Akihiko, Rahman Siamak, Shivkumar Kalyanam, Vaseghi Marmar, 野上 昭彦   +10 more
core   +2 more sources

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Phosphodiesterase Type 5 Inhibitors, Sport and Doping [PDF]

, 2017
Phosphodiesterase type 5 inhibitors (PDE5i) (e.g., sildenafil, tadalafil, vardenafil, and avanafil) are drugs commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia.
Borrione, Paolo, CECI GALANOS, Roberta, Crescioli, Clara, Di Luigi, Luigi, Duranti, Guglielmo, Sabatini, Stefania, Sansone, Andrea, Sansone, Massimiliano, Sgrò, Paolo   +8 more
core   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Effects of dexmedetomidine on cardiac electrical activity and ion currents: an experimental animal study

Türk Biyokimya Dergisi
Dexmedetomidine is a potent and highly selective alpha-2 adrenergic receptor agonist recognized for its sedative, hypnotic, analgesic, and sympatholytic properties.
Arun Funda, Ozturk Nihal, Erkan Orhan, Ozdemir Semir, Arun Oguzhan, Yanardag Sirma Basak, Ayaz Murat   +6 more
doaj   +1 more source

Sex‐related differences in the peripheral vascular response to hypoxia: Implications in health and relevance for obstructive sleep apnoea

Experimental Physiology, EarlyView.
Abstract The incidence and presentation of obstructive sleep apnoea, as well as hypertension and cardiovascular disease, have been reported to differ by sex. It is thus reasonable to propose mechanisms contributing to subsequent pathology differ by sex. This concept is supported from a pre‐pathological perspective, as sex differences have been observed
Dain W. Jacob, Sara E. Mascone, Natasha G. Boyes, Anna M. Gonsalves, Jacqueline K. Limberg   +4 more
wiley   +1 more source