Sympathetic activation during acute myocardial infarction is an important arrhythmogenic mechanism, but the role of central autonomic inputs and their modulating factors remain unclear. Using the in vivo rat-model, we examined the effects of clonidine, a
Theofilos M Kolettis +10 more
doaj +1 more source
Symptoms and Subjective Quality of Life in Post-Traumatic Stress Disorder: A Longitudinal Study [PDF]
PMCID: PMC3621668This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Giacco, D, Matanov, A, Priebe, S
core +2 more sources
Hypertension management: Old drug revisited - Cilnidipine
Cilnidipine is a promising fourth-generation calcium channel blocker which along with inhibition of the L-type Ca 2+ channels in vascular smooth muscle cells, also inhibits the N-type Ca 2+ channels in sympathetic neurons.
Soumitra Kumar
doaj +1 more source
Sympathetic activity and arterial hypertension: potential for correction
The paper is focussed on the role of increased sympathetic activation in the pathogenesis of arterial hypertension (AH), its exacerbations (hypertensive crises), and complications.
O. Yu. Shayduk, E. O. Taratukhin
doaj +1 more source
Decreasing adrenergic or sympathetic hyperactivity after severe traumatic brain injury using propranolol and clonidine (DASH After TBI Study): study protocol for a randomized controlled trial [PDF]
BACKGROUND: Severe TBI, defined as a Glasgow Coma Scale ≤ 8, increases intracranial pressure and activates the sympathetic nervous system. Sympathetic hyperactivity after TBI manifests as catecholamine excess, hypertension, abnormal heart rate ...
Ayaka Sugiura +6 more
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Dopaminergic agonist bromocriptin in treatment of diabetes mellitus type 2
Bromocriptine is a sympatholytic agonist of dopamine receptors, which is now proposed for treatment of type 2 diabetes mellitus. In animal studies bromocriptine elevates the decreased levels of dopamine in hypothalamus and blocks excessive sympathetic ...
O. A. Gerasimenko +2 more
doaj +1 more source
Adjuvant dexmedetomidine in treatment of alcohol withdrawal delirium: Case series
Alcohol withdrawal delirium is a medical emergency with mortality rates of 20–50% without treatment. Benzodiazepines (BZDs) (gamma-aminobutyric acid receptor agonists) are the mainstay of treatment.
Amit Chail +3 more
doaj +1 more source
Marijuana Legislation: Identifying the Impact on the Oral Healthcare Provider [PDF]
Objectives/Aims: Since the mid-2000s, the United States has seen a surge in legislation involving the legalization of marijuana, both recreationally and medicinally.
Geiser, Abby L, Reid-Burrell, Jessica
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Menopause and autonomic control of heart
Menopause is associated with decreased heart rate variability, which is due to reduced parasympathetic or increased sympathetic outflow to the heart. Acute myocardial infarction may be accompanied by decreased heart rate variability.
Arunima Chaudhuri, Nirmala G Borade
doaj +1 more source
Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]
BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS +6 more
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