Sympathetic Regulation of Hematopoiesis and the Mobilization of Inflammatory Cells in ICR Mice with Traumatic Brain Injury: A Novel Approach to Targeting Neuroinflammation and Degenerative Processes [PDF]
BiomedicinesBackground/Objectives: Neuroinflammation is a leading factor in secondary brain damage following a traumatic brain injury (TBI). Existing therapeutic approaches have limited efficacy against neuroinflammation.
Natalia Ermakova +6 more
doaj +2 more sources
Sympathetic overactivity and nocturnal diuresis in obstructive sleep apnea alter the response to hypertension therapy [PDF]
Clinical HypertensionBackground Obstructive sleep apnea (OSA) is associated with high blood pressure that responds poorly to usual antihypertensive therapy. Methods and results Forty-one subjects with OSA had 25% higher plasma norepinephrine and 42% higher epinephrine ...
Michael G. Ziegler +3 more
doaj +2 more sources
Dexmedetomidine for postoperative delirium in surgical patients: a mini-review of mechanisms, clinical evidence, and practical implementation [PDF]
Frontiers in PharmacologyPostoperative delirium (POD) is a common acute neurocognitive disorder in the perioperative period, significantly increasing the risks of mortality and long-term functional decline.
Xiao-yan Li +4 more
doaj +2 more sources
Central sympatholytics prolong survival in experimental sepsis [PDF]
Critical Care, 2009 Abstract Introduction One of the main causes of death in European and US intensive care units is sepsis. It involves a network of pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6. Furthermore, there is an up regulation of transcription factors such as nuclear factor (NF) κB. It has previously been
Hofer, Stefan +8 more
openaire +5 more sources
Central Sympatholytic Drugs [PDF]
Journal of Clinical Hypertension, 2011 Wanpen Vongpatanasin
exaly +2 more sources
Pediatric clonidine and guanfacine poisoning: a single-center retrospective review
Toxicology Communications, 2021 Clonidine and guanfacine are centrally acting sympatholytics (CAS). Poisoning with these agents is common in children, and management of this poisoning is controversial. We sought to characterize our experience with pediatric CAS poisonings.
Kevin Baumgartner, Michael Mullins
doaj +1 more source
ARTERIAL HYPERTENSION IN YOUNG PEOPLE: EFFICACY OF SYMPATHOLYTIC THERAPY
Рациональная фармакотерапия в кардиологии, 2015 Aim. To evaluate the effect of imidasoline agonist, rilmenidine (Albarel), on 24-hour blood pressure (BP) profile and autonomic regulation of cardiovascular system in young patients with arterial hypertension (HT) and exogenous constitutional obesity ...
N. N. Nikitina +3 more
doaj +3 more sources
Dexmedetomidine: present and future directions [PDF]
Korean Journal of Anesthesiology, 2019 Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
doaj +1 more source
Minimal Side-effects and Adequate Analgesia in Spinal Anaesthesia: A Randomised Double Blinded Study Comparing Buprenorphine and Clonidine [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Postoperative patient management includes managing the acute postoperative pain as well as the side-effects associated with the use of various medications in pain management.
DM Ramya, KN Vikas, Sudhir S Rao
doaj +1 more source
Frontiers in Pharmacology, 2021 Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially life-threatening hypotension and subsequent cardiovascular collapse.
Nhi Thuc Vuong +2 more
doaj +1 more source