Outcomes Following Radiofrequency Renal Denervation According to Antihypertensive Medications: Subgroup Analysis of the Global SYMPLICITY Registry DEFINE. [PDF]
BACKGROUND: The Global SYMPLICITY Registry DEFINE investigates radiofrequency renal denervation (RDN) in a broad range of patients with hypertension. We evaluated whether the number or type of antihypertensive medications were associated with increased ...
Mahfoud F +14 more
europepmc +3 more sources
A case report of an atypical haemolytic uremic syndrome in pregnancy: something wicked this way comes [PDF]
Background Atypical Haemolytic Uremic Syndrome is an acute life-threatening condition, characterized by the clinical triad of microangiopathic hemolytic anaemia, thrombocytopenia, kidney injury.
Stefano Catarci +6 more
doaj +2 more sources
Skin sodium content as a predictor of blood pressure response to renal denervation. [PDF]
Patients with treatment resistant hypertension (TRH) are known to have elevated sodium (Na) content in muscle and skin. Renal denervation (RDN) emerged as an adjacent therapeutic option in this group of patients. This analysis aimed at evaluating whether
Guenes-Altan M +8 more
europepmc +3 more sources
Laccases as Effective Tools in the Removal of Pharmaceutical Products from Aquatic Systems [PDF]
This review aims to provide a comprehensive overview of the application of bacterial and fungal laccases for the removal of pharmaceuticals from the environment.
Daniela Chmelová +2 more
doaj +2 more sources
Left ventricular structure and function following renal sympathetic denervation in patients with HFpEF: an echocardiographic 9-year long-term follow-up. [PDF]
Background: High blood pressure is a major risk factor for cardiac remodeling and left ventricular hypertrophy, increasing cardiovascular risk and leading to heart failure with preserved ejection fraction (HFpEF). Since renal sympathetic denervation (RDN)
Vogt A +6 more
europepmc +6 more sources
Central sympatholytics prolong survival in experimental sepsis [PDF]
Abstract Introduction One of the main causes of death in European and US intensive care units is sepsis. It involves a network of pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6. Furthermore, there is an up regulation of transcription factors such as nuclear factor (NF) κB. It has previously been
Hofer, Stefan +8 more
openaire +5 more sources
Dexmedetomidine: present and future directions [PDF]
Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
doaj +1 more source
Refractory arterial hypertension is characterized by a lack of control of target blood pressure, despite the prolonged use >5 antihypertensive drugs with different mechanisms of action, including longacting diuretic chlorthalidone and the ...
O. B. Kuzmin, V. V. Zhezha
doaj +1 more source
Attenuation of Haemodynamic Parameters in Response to Pneumoperitoneum during Laparoscopic Cholecystectomy: A Randomized Controlled Trial Comparing Infusions of Propofol and Dexmedetomidine [PDF]
Introduction: Effective control of sympathetic response to pneumoperitoneum is vital to avoid morbidity in patients undergoing laparoscopic surgeries. This control must be achieved without any side effects of the drugs being used as well as ensuring ...
Meyong Pincho Bhutia, Arati Rai
doaj +1 more source
Pediatric clonidine and guanfacine poisoning: a single-center retrospective review
Clonidine and guanfacine are centrally acting sympatholytics (CAS). Poisoning with these agents is common in children, and management of this poisoning is controversial. We sought to characterize our experience with pediatric CAS poisonings.
Kevin Baumgartner, Michael Mullins
doaj +1 more source

