Results 91 to 100 of about 13,066 (249)

Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters. [PDF]

open access: yes, 2019
Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in ...
Deutschbauer, Adam M   +4 more
core   +1 more source

MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AS SIGNALLING MOLECULES OF INTRACELLULAR PATHWAYS TRIGGERED BY THE CARDIAC RENIN-ANGIOTENSIN II-ALDOSTERONE SYSTEM (RAAS).

open access: yesFrontiers in Physiology, 2013
Mitochondria represent major sources of basal reactive oxygen species (ROS) production of the cardiomyocyte. The role of ROS as signalling molecules that mediate different intracellular pathways has gained increasing interest among physiologists in the ...
Verónica Celeste De Giusti   +5 more
doaj   +1 more source

Genome‐Wide Association Study and RNA Sequencing Identify Candidate Genes Regulating Nitrogen Use Efficiency and Associated Traits in Sorghum (Sorghum bicolor (L.) Moench)

open access: yesFood and Energy Security, Volume 15, Issue 1, January/February 2026.
ABSTRACT Sorghum (Sorghum bicolor L. Moench) is a resilient cereal crop with remarkable adaptability to diverse environments. Nitrogen use efficiency (NUE) is critical for improving sorghum yields, resource utilization, livelihood security, and environmental sustainability of the target ecologies.
Srikanth Bollam   +13 more
wiley   +1 more source

Research progress on Na+ ⁃ K+ ⁃ 2Cl- cotransporter 1 and its relationship to nervous system diseases

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Na+ ⁃ K+ ⁃ 2Cl- cotransporter 1 (NKCC1) which plays an important role in the dynamic balance of Cl- ions, is one of the cation⁃chloride cotransporter. It is a membrane protein that transferred the mediates Na+ , K+ and Cl- .
FU Xu⁃yang   +3 more
doaj  

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Genome-wide metabolic (re-) annotation of Kluyveromyces lactis [PDF]

open access: yes, 2012
Even before having its genome sequence published in 2004, Kluyveromyces lactis had long been considered a model organism for studies in genetics and physiology.
Dias, Oscar   +3 more
core   +1 more source

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]

open access: yes, 2015
Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick   +9 more
core   +3 more sources

Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status [PDF]

open access: yes, 2014
Most cancers rely on aerobic glycolysis to generate energy and metabolic intermediates. To maintain a high glycolytic rate, cells must efficiently export lactic acid through the proton-coupled monocarboxylate transporters (MCT1/4).
Baltazar, Fátima   +5 more
core   +2 more sources

Salinity-Dependent Shift in the Localization of Three Peptide Transporters along the Intestine of the Mozambique Tilapia (Oreochromis mossambicus)

open access: yesFrontiers in Physiology, 2017
The peptide transporter (PepT) systems are well-known for their importance to protein absorption in all vertebrate species. These symporters use H+ gradient at the apical membrane of the intestinal epithelial cells to mediate the absorption of small ...
Pazit Con   +3 more
doaj   +1 more source

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2. [PDF]

open access: yes, 2018
The concentration of glucose in plasma is held within narrow limits (4-10 mmol/l), primarily to ensure fuel supply to the brain. Kidneys play a role in glucose homeostasis in the body by ensuring that glucose is not lost in the urine.
Ghezzi, Chiara   +2 more
core  

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