Results 131 to 140 of about 7,540 (181)
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Mechanism of chloride interaction with neurotransmitter:sodium symporters
Nature, 2007Neurotransmitter:sodium symporters (NSS) have a critical role in regulating neurotransmission and are targets for psychostimulants, anti-depressants and other drugs. Whereas the non-homologous glutamate transporters mediate chloride conductance, in the eukaryotic NSS chloride is transported together with the neurotransmitter.
Jonathan Javitch +2 more
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Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2004
The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant.
C H, Baker, J C, Morris
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The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant.
C H, Baker, J C, Morris
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Uniporters, Symporters and Antiporters
Journal of Experimental Biology, 1994ABSTRACT Transporters are a diverse group of membrane proteins that facilitate the movement of water-soluble solutes through the lipid bilayer of biological membranes. The least complex transporters are the uniporters (Kakuda and MacLeod, 1994).
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Photosynthesis Research, 1992
The heterotrophic tissues of the plant are dependent upon carbon and nitrogen import for normal growth and development. In general, oxidized forms of these essential elements are reductively assimilated in the leaf and, subsequently, sucrose and amino acids are transported to the heterotrophic cells in a process known as assimilate partitioning.
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The heterotrophic tissues of the plant are dependent upon carbon and nitrogen import for normal growth and development. In general, oxidized forms of these essential elements are reductively assimilated in the leaf and, subsequently, sucrose and amino acids are transported to the heterotrophic cells in a process known as assimilate partitioning.
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Inhibitors of the Proton-Sucrose Symport
Archives of Biochemistry and Biophysics, 1993Sucrose transporters are important components of the assimilate partitioning pathway in many plants. In the results reported here, we examined the effect of several inhibitors on proton-coupled sucrose transport into plasma membrane vesicles isolated from sugar beet leaf tissue.
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Sodium/iodide symporter in thyroid cancer
Experimental and Clinical Endocrinology & Diabetes, 2001[No abstract available]
C. Mian +5 more
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Sodium Iodide Symporter in Health and Disease
Thyroid, 2001Radioiodine-concentrating activity in thyroid tissues has allowed the use of radioiodine as a diagnostic and therapeutic agent for patients with thyroid disorders such as well-differentiated thyroid cancer. However, some extrathyroidal tissues also take up radioiodine, contributing to unwanted side effects of radioiodine therapy.
D H, Shen +3 more
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Cloning of the Human Sodium Iodide Symporter
Biochemical and Biophysical Research Communications, 1996The iodide concentrating activity of the thyroid gland is essential to the production of thyroid hormone and also provides a mechanism for the treatment of thyroid cancer by radioiodine ablation. We report here the nucleotide and amino acid sequence of the human sodium iodide symporter (hNIS), which mediates the iodide uptake activity in the thyroid ...
P A, Smanik +6 more
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Cloning of the Mouse Sodium Iodide Symporter
Thyroid, 2001The iodide-concentrating ability of the thyroid gland is essential to the production of thyroid hormone. We report the nucleotide and amino acid sequence of the mouse sodium iodide symporter (mNIS), which mediates this activity within the thyroid gland.
L A, Pinke +5 more
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