Results 41 to 50 of about 12,546 (277)
eLife, 2018 The yeast Target of Rapamycin Complex 1 (TORC1) plays a central role in controlling growth. How amino acids and other nutrients stimulate its activity via the Rag/Gtr GTPases remains poorly understood.
Elie Saliba +5 more
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Frontiers in Microbiology, 2023 Enterococcus is able to grow in media at pH from 5.0 to 9.0 and a high concentration of NaCl (8%). The ability to respond to these extreme conditions requires the rapid movement of three critical ions: proton (H+), sodium (Na+), and potassium (K+).
Giuliana Acciarri +10 more
doaj +1 more source
Sodium-Assisted Formation of Binding and Traverse Conformations of the Substrate in a Neurotransmitter Sodium Symporter Model [PDF]
, 2014 Therapeutics designed to increase synaptic neurotransmitter levels by inhibiting neurotransmitter sodium sym- porters (NSSs) classify a strategic approach to treat brain disorders such as depression or epilepsy, however, the critical elementary steps ...
Bencsura, Ákos +4 more
core +1 more source
About P systems with symport/antiport [PDF]
Soft Computing, 2004 It is proved that four membranes su±ce to P systems with minimal symport/antiport to generate all recursively enumerable sets of numbers. It is also proved that P systems with symport/antiport without maximal par- allelism are equivalent to partially blind counter automata.
openaire +3 more sources
A potassium-proton symport in Neurospora crassa. [PDF]
The Journal of general physiology, 1986 Combined ion flux and electrophysiological measurements have been used to characterized active transport of potassium by cells of Neurospora crassa that have been moderately starved of K+ and then maintained in the presence of millimolar free calcium ions.
Michael R. Blatt +2 more
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Proteomic and Bioinformatic Profiling of Transporters in Higher Plant Mitochondria
Biomolecules, 2020 To function as a metabolic hub, plant mitochondria have to exchange a wide variety of metabolic intermediates as well as inorganic ions with the cytosol.
Ian Max Møller +4 more
doaj +1 more source
A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection [PDF]
, 2016 Background: Polymicrobial infections represent a great challenge for the clarification of disease etiology and the development of comprehensive diagnostic or therapeutic tools, particularly for fastidious and difficult-to-cultivate bacteria. Using bovine
Boye, Mette +7 more
core +6 more sources
Expression of the sodium iodide symporter in human kidney [PDF]
Kidney International, 2001 The human sodium iodide symporter (hNIS) is a transmembrane protein that mediates the active transport of iodide in the thyroid gland. Following cloning of NIS, NIS expression has been detected in a broad range of nonthyroidal tissues, suggesting that iodide transport in these tissues is conferred by the expression of functional NIS protein.The aim of ...
Charyl M. Dutton +6 more
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Symport and antiport mechanisms of human glutamate transporters
Nature Communications, 2023 AbstractExcitatory amino acid transporters (EAATs) uptake glutamate into glial cells and neurons. EAATs achieve million-fold transmitter gradients by symporting it with three sodium ions and a proton, and countertransporting a potassium ion via an elevator mechanism. Despite the availability of structures, the symport and antiport mechanisms still need
Biao Qiu, Olga Boudker
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eLife, 2017 The Neurotransmitter:Sodium Symporters (NSSs) represent an important class of proteins mediating sodium-dependent uptake of neurotransmitters from the extracellular space.
Simon Erlendsson +9 more
doaj +1 more source