Results 81 to 90 of about 2,284,312 (360)

Assessing the representativeness of large medical data using population stability index

BMC Medical Research Methodology
Background Understanding sample representativeness is key to interpreting findings from epidemiological research and applying these findings to broader populations.
Sheng-Chieh Lu, Wenye Song, Andre Pfob, Chris Gibbons   +3 more
doaj   +1 more source

Prevalence of Mental Health Disorder Symptoms and Rates of Help-seeking Among University-Enrolled, Black Men [PDF]

, 2020
Background. Black men in college represent a subgroup of emerging adults who are at increased risk of developing mental health disorders (MHDs), such as anxiety and depression.
Adkins, Amy, Carlyle, Kellie E., Dick, Danielle, Guidry, Jeanine P. D., I-Chun Kuo, Sally, LaRose, Jessica G., Utsey, Shawn O., Williams, Kofoworola D. A., Working Group, Spit for Science   +8 more
core   +1 more source

Development of a Short Trauma Screening Tool (STST) to Measure Child Trauma Symptoms: Establishing Content Validity [PDF]

, 2019
Purpose: The purpose of the study was to identify major symptom domain variables common to child trauma and create a prototype short trauma symptom screening tool (STST) intended for use in pediatric medical settings.
Allison, Jeroan J., MS MD, Forkey, Heather C., MD, Hirsh, Estelle, BA, Maguire, Laura L., RN MS PhD   +3 more
core   +2 more sources

Symptoms? Which Symptoms? Distorted Symptom Presentation and Its Detection

In this chapter, we elaborated on the two main forms of distorted symptom reporting: symptom over- and underreporting. In certain situations, individuals might exaggerate their symptoms. For instance, defendants facing legal issues may overstate their mental health problems.
Merckelbach, Harald, Boškovic, Irena
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Role of patient-reported outcomes in geriatric oncology research and patient care

Holistic Integrative Oncology
Health-related quality of life (HRQOL) and daily functioning are central considerations for older adults with cancer. Attention to symptom burden, daily functioning, and HRQOL is imperative in this patient population to identify relevant research ...
Xin Shelley Wang, Charles S. Cleeland
doaj   +1 more source

The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. [PDF]

, 2014
BACKGROUND: Unlike other respiratory infections, tuberculosis diagnoses increase in summer. We performed an ecological analysis of this paradoxical seasonality in a Peruvian shantytown over 4 years. METHODS: Tuberculosis symptom-onset and diagnosis dates
Adams, Akhtar, Ane-Anyangwe, Anibarro, Arnedo-Pena, Baker, C. A. Evans, C. Jongkaewwattana, Chew, Dowling, Drucker, E. S. Ramos, Ford, G. Sandhu, J. J. Lewis, J. S. Friedland, K. Zevallos, Kennel, Liu, Lonnroth, Luquero, M. A. Tovar, M. R. Baldwin, Martineau, Nagayama, Onifade, Parrinello, R. H. Gilman, R. Montoya, Rao, Rook, S. G. Schumacher, Schaaf, Stamp, T. Wingfield, ten Asbroek, Wilkinson, Yang, Yoshiyama   +38 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]

, 2019
Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill, Gunter, Jeffrey L, Haley, Dana, Jones, David, Kantarci, Kejal, Knopman, David, Kraft, Ruth, Lapid, Maria, Lesnick, Timothy, Rademakers, Rosa, Rosen, Howie, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +22 more
core   +3 more sources