Solvent Effects on the Conformational Preferences of 2,6‐Pyridylcarboxamide Foldamers
The marked effect of organic solvents and water/methanol mixtures on the conformational preferences of a soluble chiral foldamer has been established in a diverse array of seventeen distinct environments. ABSTRACT The marked influence of organic solvents and water on the conformational preferences of a chiral, soluble 2,6‐pyridylcarboxamide foldamer ...
Alexander R. Davis +5 more
wiley +1 more source
Enrichment and amplification of secreted α-synuclein from cellular model and saliva of patients with synucleinopathies. [PDF]
Xu W, Luan M, Wang Z, Deng J, Zhu L.
europepmc +1 more source
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Synaptic vesicle architecture modulates α-synuclein conformation and pathogenic transitions in Parkinson's disease. [PDF]
Ranjan P.
europepmc +1 more source
Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern +4 more
wiley +1 more source
Progress of Immunotherapies in Parkinson's Disease. [PDF]
Peng Y +10 more
europepmc +1 more source
A one‐shot Pd(II)‐catalyzed C─H activation strategy enables the rapid conversion of simple linear propiolamides into structurally diverse mono‐, di‐, and tri‐olefin‐bridged MPAEs. This cascade process orchestrates up to six sequential C–H activations in a single operation, providing streamlined access to highly conjugated architectures.
Haiyu Wang +4 more
wiley +1 more source
Fil: Castillo, Daniela Susana. Universidad de San Andrés. Escuela de Negocios; Argentina.
openaire +1 more source
Synthesis and Structure of an S‐Shaped Double Expanded Helicene With Seven Fused Anthracene Units
The anthracene‐fused aromatic compound was synthesized by four‐fold cycloisomerization of the corresponding alkyne precursor. X‐ray crystallographic analysis revealed that this compound had a double helical structure of Ci symmetry, in which the terminal and central anthracene units were triply stacked.
Shinji Toyota +6 more
wiley +1 more source
Connexin 50 mediates disease-relevant alpha-synuclein oligomer propagation and neuroinflammation in neurodegenerative disease. [PDF]
Puangmalai N +12 more
europepmc +1 more source

