Results 111 to 120 of about 175,000 (211)

Deletion or immunotherapeutic blockade of FcγRIIb (CD32b) impairs α-Syn propagation in vivo. [PDF]

Acta Neuropathol
Hennegan JM, Hurley MJ, Colley M, Cox KL, Douglas LR, Duriez PJ, Oldham RJ, Cragg MS, Frendéus B, Roghanian A, Teeling JL.   +10 more
europepmc   +1 more source

Enabling Cross‐Coupling Reactivity of α‐Pentafluorosulfanyl Compounds with a Thermally Stable Organozinc α‐SF5 Reagent

Chemistry – A European Journal, EarlyView.
This work describes the first example of a thermally stable α‐SF5 organometallic reagent, which allows for extensive downstream functionalization by allylation and acylation reactions under copper catalysis, as well as palladium‐catalyzed Negishi‐type cross‐coupling conditions up to 96% yield. In silico analysis shines initial light on the requirements
Lujie Xu, David Rombach
wiley   +1 more source

Tribenzotriquinacene Fused Dimers (“Fusodimers”)—Synthesis and Host–Guest Properties

Chemistry – A European Journal, EarlyView.
Two tribenzotriquinacene units merged with each other in either syn‐ or anti‐orientation of the bowls have become accessible in a short synthesis. In contrast to the anti‐isomer, the syn‐isomer forms 1:1 host–guest complexes with both C60 and C70 in solution and in the solid state, as shown by 1H NMR spectroscopy and x‐ray diffraction.
Chun‐Fai Ng, Lisi He, Yin‐Ying Cheung, Xiao‐Ping Cao, Dietmar Kuck, Hak‐Fun Chow   +5 more
wiley   +1 more source

Blood-Mediated Gut-Brain Axis in Parkinson's Disease: Focus on α-Synuclein Transport and Microbiota Dysbiosis-Induced Inflammation. [PDF]

Cells
Xu C, Li W, Ma X, Han L, Cui G, Zhao J, Wang X, Guan Y.   +7 more
europepmc   +1 more source

Non‐Covalent Fluorine–Silica Anchoring of a Molecular Platinum(II) bis(NHC) Catalyst: Structure, Interface Control, and Hydrosilylation Activity

Chemistry – A European Journal, EarlyView.
A Pt(II) bis(NHC) complex is immobilized on mesoporous silica through directional F–Si interactions encoded in the ligand framework. Quantitative 19F{29Si} REDOR experiments and molecular dynamics simulations establish Å‐scale catalyst–support contacts and define the interfacial organization.
Alexander Bergen, Cindy‐Ly Tavera‐Méndez, Valentina Eichhorn, Philip Maier, Elias Harrer, Andreas Scheurer, Frank W. Heinemann, Dirk Zahn, Martin Hartmann, Dorothea Wisser, Karsten Meyer   +10 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

When Pathologies Collide: The Intersection of Tau and Alpha-Synuclein in Neurodegenerative Diseases. [PDF]

Mol Neurobiol
Hunt JN, Kortagere S.
europepmc   +1 more source

Designing a Triplet 2‐Formylphenylnitrene With Fast Tunneling Reactivity

Chemistry – A European Journal, EarlyView.
A 3‐CF3 substituent accelerates tunneling in triplet 2‐formylphenylnitrene, making its reactivity in cryogenic matrices too fast for conventional IR spectroscopic detection. Bringing this chemistry to low‐temperature solutions allows suppression of intrinsic nitrene dimerization through faster cyclization, which even outcompetes the 1,4‐H shift ...
Sofia Braz, Cláudio M. Nunes, Simon Schlosser, Peter R. Schreiner, Rui Fausto   +4 more
wiley   +1 more source

Hidden in Plain Sight: Aromaticity of Hexagonal Boron Nitride

Chemistry – A European Journal, EarlyView.
How apt is the nickname “white graphene” for hexagonal boron nitride (hBN)? Although graphene's aromaticity is well established, it is not known if hBN is aromatic. In this work, hBN's aromaticity is probed using magnetic and energetic criteria. Group‐theoretic considerations and magnetically induced current density maps are used to further reveal the ...
Suryakanti Debata, Sai Krishna Narayanan, Pratibha Dev   +2 more
wiley   +1 more source

AZP2006 in Parkinson's disease models: A promising new neuroprotective treatment involving lysosomal homeostasis and the Progranulin/Prosaposin complex. [PDF]

PLoS One
Callizot N, Culley G, Flower G, Rouvière L, De Conto V, Wojcinski A, Botto C, Estrella C, Henriques A, Verwaerde P.   +9 more
europepmc   +1 more source