Results 121 to 130 of about 449,578 (382)

Astrocytes Control Synapse Formation, Function, and Elimination.

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Astrocytes, through their close associations with synapses, can monitor and alter synaptic function, thus actively controlling synaptic transmission in the adult brain. Besides their important role at adult synapses, in the last three decades a number of
Won-Suk Chung, N. J. Allen, C. Eroglu
semanticscholar   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

open access: yesAdvanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou   +5 more
wiley   +1 more source

Clustered synapses develop in distinct dendritic domains in visual cortex before eye opening

open access: yeseLife
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites are activated by similar stimuli.
Alexandra H Leighton   +2 more
doaj   +1 more source

Electrical synapses and their functional interactions with chemical synapses [PDF]

open access: yesNature Reviews Neuroscience, 2014
Brain function relies on the ability of neurons to communicate with each other. Interneuronal communication primarily takes place at synapses, where information from one neuron is rapidly conveyed to a second neuron. There are two main modalities of synaptic transmission: chemical and electrical. Far from functioning independently and serving unrelated
openaire   +3 more sources

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Synapses: Glia help synapses form and function [PDF]

open access: yesCurrent Biology, 1998
AbstractA sophisticated new cell-culture system has shown that glial cells can promote synaptogenesis and enhance the efficacy of synaptic transmission. These effects are not secondary to increased neuronal survival but probably involve changes in neuronal activity levels and a secreted glial factor.
openaire   +2 more sources

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

open access: yesAdvanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung   +8 more
wiley   +1 more source

Characterisation of the Volatile Compounds and Key Odourants in Japanese Mandarins by Gas Chromatography–Mass Spectrometry and Gas Chromatography–Olfactometry

open access: yesSeparations
Japanese mandarins are becoming increasingly popular due to their pleasant aroma. The volatiles in four varieties of Japanese mandarins (Iyokan, Ponkan, Shiranui, and Unshiu mikan) were extracted by headspace solid-phase microextraction (HS-SPME) and ...
Lingyi Li   +9 more
doaj   +1 more source

Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

open access: yesJournal of Neuroscience, 2007
Alzheimer's disease (AD) is characterized by decreased synapse density in hippocampus and neocortex, and synapse loss is the strongest anatomical correlate of the degree of clinical impairment.
G. Shankar   +5 more
semanticscholar   +1 more source

Symmetry Enhanced Unconventional Spin Current Anisotropy in a Collinear Antiferromagnet

open access: yesAdvanced Functional Materials, EarlyView.
Spin‐orbit torques (SOTs) are investigated in epitaxial FeSn, a topological antiferromagnet with kagome lattice symmetry. Combining experimental and theoretical approaches, the study identifies a six‐fold conventional damping‐like spin‐orbit torque (DL SOT), along with the coexistence of both six‐fold and uniaxial unconventional field‐like torque (FL ...
Pankhuri Gupta   +10 more
wiley   +1 more source

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