Results 61 to 70 of about 1,630,780 (295)
Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination [PDF]
The Journal of Neuroscience, 2016 At birth, each mammalian skeletal muscle fiber is innervated by multiple motor neurons, but in a few weeks, all but one of those axons retracts (Redfern, 1970) and differential activity between inputs controls this phenomenon (Personius and Balice-Gordon, 2001; Sanes and Lichtman, 2001; Personius et al., 2007; Favero et al., 2012).
Kirkwood E. Personius +2 more
openaire +2 more sources
Frontiers in Cellular Neuroscience, 2019 Neuronal activity is thought to drive the remodeling of circuits in the mammalian cerebral cortex. However, its precise function in the underlying formation and elimination of glutamatergic synapses has remained controversial.
Dylan P. Quinn +6 more
doaj +1 more source
Four-quadrant one-transistor-synapse for high-density CNN implementations [PDF]
, 1998 Presents a linear four-quadrants, electrically-programmable, one-transistor synapse strategy applicable to the implementation of general massively-parallel analog processors in CMOS technology.
Carmona Galán, Ricardo +3 more
core +1 more source
Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo [PDF]
, 2016 Whether neurons can restore their original connectivity patterns during circuit repair is unclear. Taking advantage of the regenerative capacity of zebrafish retina, we show here the remarkable specificity by which surviving neurons reassemble their ...
A Carleton +49 more
core +1 more source
Cell Reports, 2014 Experience refines synaptic connectivity through neural activity-dependent regulation of transcription factors. Although activity-dependent regulation of transcription factors has been well described, it is unknown whether synaptic activity and local ...
Julia R. Wilkerson +8 more
doaj +1 more source
Cell Reports, 2015 Synapse elimination occurs in development, plasticity, and disease. Although the importance of synapse elimination has been documented in many studies, the molecular mechanisms underlying this process are unclear.
Lingfeng Meng +6 more
doaj +1 more source
Cell Reports, 2014 Synapse elimination is crucial for precise neural circuit formation during postnatal development. We examined how relative differences in synaptic strengths among competing inputs and/or absolute synaptic strengths contribute to climbing fiber (CF) to ...
Shinya Kawata +8 more
doaj +1 more source
VLSI implementation of a transconductance mode continuous BAM with on chip learning and dynamic analog memory [PDF]
, 1991 In this paper we present a complete VLSI Continuous-Time Bidirectional Associative Memory (BAM). The short term memory (STM) section is implemented using small transconductance four quadrant multipliers, and capacitors for the integrators.
Huertas Díaz, José Luis +3 more
core +1 more source
Microglial MERTK eliminates phosphatidylserine‐displaying inhibitory post‐synapses
The EMBO Journal, 2021 Glia contribute to synapse elimination through phagocytosis in the central nervous system. Despite the important roles of this process in development and neurological disorders, the identity and regulation of the "eat-me" signal that initiates glia-mediated phagocytosis of synapses has remained incompletely understood.
Jungjoo Park +5 more
openaire +2 more sources
The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
Cell Reports, 2018 Summary: Aging brains undergo cognitive decline, associated with decreased neuronal synapse number and function and altered metabolism. Astrocytes regulate neuronal synapse formation and function in development and adulthood, but whether these properties
Matthew M. Boisvert +3 more
doaj +1 more source