Results 71 to 80 of about 352,422 (329)

Neuromorphic Learning towards Nano Second Precision [PDF]

open access: yes, 2013
Temporal coding is one approach to representing information in spiking neural networks. An example of its application is the location of sounds by barn owls that requires especially precise temporal coding. Dependent upon the azimuthal angle, the arrival
Meier, Karlheinz   +3 more
core   +1 more source

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

open access: yesAdvanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung   +8 more
wiley   +1 more source

Monoacylated Cellular Prion Proteins Reduce Amyloid-β-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage

open access: yesBiology, 2015
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) and the loss of synapses. Aggregation of the cellular prion protein (PrPC) by Aβ oligomers induced synapse damage in cultured neurons.
Ewan West   +3 more
doaj   +1 more source

Aligning a Synapse [PDF]

open access: yesNeuron, 2017
Synaptic communication requires alignment of transmitter release sites with transmitter receptors. In this issue of Neuron, Wang et al. (2017) show that α2δ4 subunits link calcium channels to a trans-synaptic complex with glutamate receptors at the visual system's first synapse.
openaire   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Storage Capacity Diverges with Synaptic Efficiency in an Associative Memory Model with Synaptic Delay and Pruning [PDF]

open access: yes, 2003
It is known that storage capacity per synapse increases by synaptic pruning in the case of a correlation-type associative memory model. However, the storage capacity of the entire network then decreases. To overcome this difficulty, we propose decreasing
Miyoshi, Seiji, Okada, Masato
core  

Controlling chaos in diluted networks with continuous neurons

open access: yes, 2000
Diluted neural networks with continuous neurons and nonmonotonic transfer function are studied, with both fixed and dynamic synapses. A noisy stimulus with periodic variance results in a mechanism for controlling chaos in neural systems with fixed ...
Caroppo D.   +11 more
core   +1 more source

Beta-rhythm oscillations and synchronization transition in network models of Izhikevich neurons: effect of topology and synaptic type [PDF]

open access: yes, 2018
Despite their significant functional roles, beta-band oscillations are least understood. Synchronization in neuronal networks have attracted much attention in recent years with the main focus on transition type.
Khoshkhou, Mahsa, Montakhab, Afshin
core   +2 more sources

Decoding Synapses [PDF]

open access: yesThe Journal of Neuroscience, 1996
The strength of many synapses is modified by various use and time-dependent processes, including facilitation and depression. A general description of synaptic transfer characteristics must account for the history-dependence of synaptic efficacy and should be able to predict the postsynaptic response to any temporal pattern of presynaptic activity.
K, Sen   +3 more
openaire   +2 more sources

Mimicking Synaptic Plasticity: Optoionic MoS2 Memory Powered by Biopolymer Hydrogels as a Dynamic Cations Reservoir

open access: yesAdvanced Functional Materials, EarlyView.
Janus (MoS2) transistors functionalized with sodium alginate (SA) and poly(vinylidene fluoride‐co‐trifluoroethylene) [P(VDF‐TrFE)] exhibit persistent photo‐induced ionic gating, driven by dynamic cation migration at the hybrid interface. This ionic mechanism enables finely tunable photoconductivity and emulates key synaptic plasticity behaviors ...
Yeonsu Jeong   +5 more
wiley   +1 more source

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