Results 1 to 10 of about 1,202 (102)

All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote. [PDF]

open access: goldPLoS Genetics, 2005
The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog.
Wei J Gong, Kim S McKim, R Scott Hawley
doaj   +4 more sources

Transcriptomic profile of epileptic children treated with ketogenic therapies [PDF]

open access: yesJournal of Integrative Neuroscience, 2022
Background: Ketogenic dietary therapies (KDT) are used as a treatment in childhood epilepsy. However, their mechanism has not yet been established. The main objective of this study was to determine the changes in the transcriptomic profile induced by ...
Jana Ruiz-Herrero   +8 more
doaj   +1 more source

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations

open access: yesFrontiers in Pharmacology, 2022
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the central nervous system, is involved in microglial homeostasis and metabolism, whose disturbances have been demonstrated to play a key role in memory ...
Triana Espinosa-Jiménez   +33 more
doaj   +1 more source

Mad1's ability to interact with Mad2 is essential to regulate and monitor meiotic synapsis in C. elegans.

open access: yesPLoS Genetics, 2021
Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle checkpoint components, Mad1 and Mad2, and ...
Alice Devigne, Needhi Bhalla
doaj   +1 more source

Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis. [PDF]

open access: yesPLoS Genetics, 2013
Reduction in ploidy to generate haploid gametes during sexual reproduction is accomplished by the specialized cell division program of meiosis. Pairing between homologous chromosomes and assembly of the synaptonemal complex at their interface (synapsis ...
Susanna Mlynarczyk-Evans   +2 more
doaj   +1 more source

A Compact Fully Electronically Tunable Memristive Circuit Based on CCCDTA with Experimental Results

open access: yesMicromachines, 2023
This work presents a flux-controlled memristor structure employing a Current-Controlled Current Differencing Transconductance Amplifier (CCCDTA) with a grounded capacitor.
Deniz Ozenli
doaj   +1 more source

Photonic neural networks based on integrated silicon microresonators [PDF]

open access: yesIntelligent Computing 30 Nov 2023, 2023
The recent progress of artificial intelligence (AI) has boosted the computational possibilities in fields where standard computers are not able to perform. The AI paradigm is to emulate human intelligence and therefore breaks the familiar architecture on which digital computers are based.
arxiv   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

open access: yesFrontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio   +3 more
doaj   +1 more source

The Formation of Bivalents and the Control of Plant Meiotic Recombination

open access: yesFrontiers in Plant Science, 2021
During the first meiotic division, the segregation of homologous chromosomes depends on the physical association of the recombined homologous DNA molecules.
Yared Gutiérrez Pinzón   +3 more
doaj   +1 more source

The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior

open access: yesFrontiers in Cell and Developmental Biology, 2022
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive and nonfunctional synapses and
I. Suárez-Pereira   +15 more
doaj   +1 more source

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