Failure of homologous synapsis and sex-specific reproduction problems [PDF]
Frontiers in Genetics, 2012 The prophase of meiosis I ensures the correct segregation of chromosomes to each daughter cell. This includes the pairing, synapsis and recombination of homologous chromosomes. A subset of chromosomal abnormalities, including translocation and inversion,
Hiroki eKurahashi +4 more
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Accumulation of ph1 (zip4-5B) and ph2 (msh7-3D) mutations fails to boost homoeologous recombination in hexaploid wheat [PDF]
Frontiers in Plant ScienceDiversification of the hexaploid (bread) wheat genetic pool using wild genetic resources relies on effective meiotic recombination (crossover) between wheat chromosomes and their counterparts from related species (homoeologues).
Camille Haquet +9 more
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Somatic Kitl promotes mTOR to facilitate prophase I of meiosis in female embryonic gonads [PDF]
Cell Death and DiseaseHomologous synapsis and recombination are the central events that take place in the prophase I of meiosis. Signaling that promotes the germ cell differentiation and prophase I remains elusive.
Chang Liu +11 more
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The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
Nature Communications, 2019 During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB ...
Bailin Zhao +2 more
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, 2018 Published as part of Bui, Van Bac & Bonkowski, Michael, 2018, Synapsis puluongensis sp. nov. and redescription of S. horaki (Coleoptera: Scarabaeidae), with a key to Vietnamese species, pp. 407-418 in Acta Entomologica Musei Nationalis Pragae (Acta. Ent. Mus. Natl. Pragae) (Acta. Ent. Mus. Natl.
Bui, Van Bac, Bonkowski, Michael
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Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization [PDF]
The EMBO JournalIn mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown.
Dongteng Liu +18 more
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Chromosome segregation in plant meiosis [PDF]
Frontiers in Plant Science, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
Linda eZamariola +4 more
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The role of DNA dependent protein kinase in synapsis of DNA ends [PDF]
Nucleic Acids Research, 2003 Jan H J Hoeijmakers, Dik C Van Gent
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Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility [PDF]
Science Advances, 2020 Fernando Sánchez-Sáez +2 more
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The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance. [PDF]
, 2013 For most organisms, chromosome segregation during meiosis relies on deliberate induction of DNA double-strand breaks (DSBs) and repair of a subset of these DSBs as inter-homolog crossovers (COs).
Dernburg, Abby +6 more
core +18 more sources