Results 11 to 20 of about 23,521 (333)

Transcriptomic profile of epileptic children treated with ketogenic therapies [PDF]

Journal of Integrative Neuroscience, 2022
Background: Ketogenic dietary therapies (KDT) are used as a treatment in childhood epilepsy. However, their mechanism has not yet been established. The main objective of this study was to determine the changes in the transcriptomic profile induced by ...
Jana Ruiz-Herrero, Gloria Olaso-Gonzalez, Eva Serna, Elvira Cañedo-Villarroya, Angela G. Correas, Juan Gambini, Mari Carmen Gomez-Cabrera, Consuelo Pedrón-Giner, Jose Vina   +8 more
doaj   +1 more source

Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair. [PDF]

Biophys Rep
Jiang Y, Zhao C, Zhang C, Li W, Liu D, Zhao B.   +5 more
europepmc   +2 more sources

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

Frontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio, Heïdi Serra, Pierre Sourdille, James D. Higgins   +3 more
doaj   +1 more source

Oligomerisation of Ku from Mycobacterium tuberculosis promotes DNA synapsis. [PDF]

Nat Commun
Zahid S, Baconnais S, Smith H, Atwal S, Bates L, Read H, Chadda A, Morati F, Bedwell T, Stender EGP, Walter J, Hardwick SW, Westerlund F, Galburt E, Le Cam E, Pyne A, Mukamolova GV, Chaplin AK.   +17 more
europepmc   +3 more sources

Improved synapsis dynamics accompany meiotic stability in <i>Arabidopsis arenosa</i> autotetraploids. [PDF]

Proc Natl Acad Sci U S A
Gonzalo A, Nayak A, Bomblies K.
europepmc   +3 more sources

Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis. [PDF]

PLoS Genetics, 2013
Reduction in ploidy to generate haploid gametes during sexual reproduction is accomplished by the specialized cell division program of meiosis. Pairing between homologous chromosomes and assembly of the synaptonemal complex at their interface (synapsis ...
Susanna Mlynarczyk-Evans, Baptiste Roelens, Anne M Villeneuve   +2 more
doaj   +1 more source

A Compact Fully Electronically Tunable Memristive Circuit Based on CCCDTA with Experimental Results

Micromachines, 2023
This work presents a flux-controlled memristor structure employing a Current-Controlled Current Differencing Transconductance Amplifier (CCCDTA) with a grounded capacitor.
Deniz Ozenli
doaj   +1 more source

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations

Frontiers in Pharmacology, 2022
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the central nervous system, is involved in microglial homeostasis and metabolism, whose disturbances have been demonstrated to play a key role in memory ...
Triana Espinosa-Jiménez, Triana Espinosa-Jiménez, Triana Espinosa-Jiménez, Oriol Busquets, Amanda Cano, Amanda Cano, Amanda Cano, Amanda Cano, Elena Sánchez-López, Elena Sánchez-López, Elena Sánchez-López, Elena Sánchez-López, Ester Verdaguer, Ester Verdaguer, Ester Verdaguer, Antoni Parcerisas, Jordi Olloquequi, Carme Auladell, Carme Auladell, Carme Auladell, Jaume Folch, Jaume Folch, Walter Wahli, Walter Wahli, Walter Wahli, Manuel Vázquez-Carrera, Manuel Vázquez-Carrera, Manuel Vázquez-Carrera, Antoni Camins, Antoni Camins, Antoni Camins, Miren Ettcheto, Miren Ettcheto, Miren Ettcheto   +33 more
doaj   +1 more source

The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior

Frontiers in Cell and Developmental Biology, 2022
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive and nonfunctional synapses and
I. Suárez-Pereira, I. Suárez-Pereira, I. García-Domínguez, L. Bravo, M. Santiago, J. García-Revilla, A. M. Espinosa-Oliva, I. M. Alonso-Bellido, C. López-Martín, E. M. Pérez-Villegas, J. A. Armengol, E. Berrocoso, E. Berrocoso, J. L. Venero, R. M. de Pablos, R. Ruiz   +15 more
doaj   +1 more source

Regulation of microglia phagocytosis and potential involvement of exercise

Frontiers in Cellular Neuroscience, 2022
Microglia are considered the main phagocytic cells in the central nervous system, remodeling neural circuits by pruning synapses during development. Microglial phagocytosis is also a crucial process in maintaining adult brain homeostasis and clearing ...
Congqin Li, Yong Wang, Ying Xing, Jing Han, Yuqian Zhang, Anjing Zhang, Jian Hu, Yan Hua, Yulong Bai, Yulong Bai, Yulong Bai   +10 more
doaj   +1 more source