Results 221 to 230 of about 23,706 (334)

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

open access: yesAdvanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu   +20 more
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

open access: yesAdvanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang   +5 more
wiley   +1 more source

Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor

open access: yesAdvanced Science, EarlyView.
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid   +12 more
wiley   +1 more source

Topological Defects in Carbon Matrix Are Efficiently Constructed by Joule Thermal Shock for Catalyzing the Growth of Carbon Nanotubes

open access: yesAdvanced Science, EarlyView.
The Joule thermal shock technique ensures the efficient construction of topological defects in the carbon matrix because the instantaneous cooling suppresses the graphitization rearrangement of the heteroatom removal sites. This topological defect carbon can activate carbon source molecules by electron transfer, and further grow into carbon nanotubes ...
Bin Wang   +9 more
wiley   +1 more source

Chromatin remodeler ISW-1 orchestrates chromosome axis assembly and meiotic progression in C. elegans. [PDF]

open access: yesNucleic Acids Res
Wang R   +8 more
europepmc   +1 more source

Integration of Freestanding High‐k Oxide Membranes for 2D Ferroelectric Field‐Effect Transistors

open access: yesAdvanced Science, EarlyView.
This work introduces a defect‐tolerant integration strategy that enables freestanding BaTiO3 membranes to form low‐leakage top‐gate junctions with MoS2. The resulting FeFETs exhibit a record 0.22 V nm−1 memory window, ultrahigh‐k response, and near‐ideal subthreshold swings.
Zejing Guo   +16 more
wiley   +1 more source

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