The Formation of Bivalents and the Control of Plant Meiotic Recombination
Frontiers in Plant Science, 2021 During the first meiotic division, the segregation of homologous chromosomes depends on the physical association of the recombined homologous DNA molecules.
Yared Gutiérrez Pinzón +3 more
doaj +1 more source
Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion [PDF]
, 2005 Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription.
Dekker, Cees +5 more
core +2 more sources
Rad54: the Swiss Army knife of homologous recombination? [PDF]
, 2006 Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich +3 more
core +2 more sources
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase. [PDF]
, 2016 DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase ...
Johnson, Reid C +4 more
core +1 more source
Female Meiosis: Synapsis, Recombination, and Segregation in Drosophila melanogaster
Genetics, 2018 A century of genetic studies of the meiotic process in Drosophila melanogaster females has been greatly augmented by both modern molecular biology and major advances in cytology.
S. Hughes +3 more
semanticscholar +1 more source
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. [PDF]
PLoS Genetics, 2012 Meiotic recombination and chromosome synapsis between homologous chromosomes are essential for proper chromosome segregation at the first meiotic division. While recombination and synapsis, as well as checkpoints that monitor these two events, take place
Tomoyuki Fukuda +5 more
doaj +1 more source
Telomere distribution pattern and synapsis initiation during spermatogenesis in zebrafish [PDF]
Developmental Dynamics, 2014 Kenji Saito +3 more
openalex +2 more sources
Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing.
PLoS Genetics, 2019 During meiosis, each chromosome must selectively pair and synapse with its own unique homolog to enable crossover formation and subsequent segregation.
Talia Hatkevich +5 more
doaj +1 more source
Tau oligomers: the toxic player at synapses in Alzheimer’s disease
Frontiers in Cellular Neuroscience, 2015 Alzheimer’s disease (AD) is a progressive disorder in which the most noticeable symptoms are cognitive impairment and memory loss. However, the precise mechanism by which those symptoms develop remains unknown.
Marcos Jair Guerrero-Munoz +2 more
doaj +1 more source
Defending the genome from the enemy within:mechanisms of retrotransposon suppression in the mouse germline [PDF]
, 2013 The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable ...
A Aravin +241 more
core +1 more source