Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing.
PLoS Genetics, 2019 During meiosis, each chromosome must selectively pair and synapse with its own unique homolog to enable crossover formation and subsequent segregation.
Talia Hatkevich +5 more
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Meiotic Synapsis in the Absence of Recombination [PDF]
Science, 1998 Although in Saccharomyces cerevisiae the initiation of meiotic recombination, as indicated by double-strand break formation, appears to be functionally linked to the initiation of synapsis, meiotic chromosome synapsis in Drosophila females occurs in the absence of meiotic exchange.
Jeff Sekelsky +6 more
openaire +3 more sources
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. [PDF]
PLoS Genetics, 2012 Meiotic recombination and chromosome synapsis between homologous chromosomes are essential for proper chromosome segregation at the first meiotic division. While recombination and synapsis, as well as checkpoints that monitor these two events, take place
Tomoyuki Fukuda +5 more
doaj +1 more source
Synapsis of loxP Sites by Cre Recombinase [PDF]
Journal of Biological Chemistry, 2007 Cre recombinase catalyzes site-specific recombination between 34-bp loxP sites in a variety of topological and cellular contexts. An obligatory step in the recombination reaction is the association, or synapsis, of Cre-bound loxP sites to form a tetrameric protein assembly that is competent for strand exchange.
Feng Guo +2 more
openaire +2 more sources
Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.
, 2020 In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U. +6 more
core +1 more source
Dual effect of the wheat Ph1 locus on chromosome synapsis and crossover
Chromosoma, 2017 Allopolyploids must possess a mechanism for facilitating synapsis and crossover (CO) between homologues, in preference to homoeologues (related chromosomes), to ensure successful meiosis.
Azahara C. Martín +3 more
semanticscholar +2 more sources
Dynamics of rye chromosome 1R regions with high or low crossover frequency in homology search and synapsis development. [PDF]
PLoS ONE, 2012 In many organisms, homologous pairing and synapsis depend on the meiotic recombination machinery that repairs double-strand DNA breaks (DSBs) produced at the onset of meiosis.
Nohelia T Valenzuela +2 more
doaj +1 more source
Ultrastructural analysis of chromatin in meiosis I plus II of rye (Secale cereale L.) [PDF]
, 2004 Scanning electron microscopy (SEM) proves to be an appropriate technique for imaging chromatin organization in meiosis I and II of rye (Secale cereale) down to a resolution of a few nanometers.
Herrmann, Reinhold G. +3 more
core +1 more source
Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. [PDF]
PLoS Genetics, 2013 Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereafter, in
Uddipta Biswas +6 more
doaj +1 more source
Crossover interference mechanism: New lessons from plants
Frontiers in Cell and Developmental Biology, 2023 Plants are the source of our understanding of several fundamental biological principles. It is well known that Gregor Mendel discovered the laws of Genetics in peas and that maize was used for the discovery of transposons by Barbara McClintock.
Nahid Rafiei, Arnaud Ronceret
doaj +1 more source