Results 41 to 50 of about 23,521 (333)
Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2. [PDF]
, 2017 The HORMA domain is a highly conserved protein-protein interaction module found in eukaryotic signaling proteins including the spindle assembly checkpoint protein Mad2 and the meiotic HORMAD proteins.
Corbett, Kevin D +2 more
core +2 more sources
Meiotic Synapsis in the Absence of Recombination [PDF]
Science, 1998 Although in Saccharomyces cerevisiae the initiation of meiotic recombination, as indicated by double-strand break formation, appears to be functionally linked to the initiation of synapsis, meiotic chromosome synapsis in Drosophila females occurs in the absence of meiotic exchange.
K S, McKim +6 more
openaire +2 more sources
Meiotic behavior of small chromosomes in maize
Frontiers in Plant Science, 2013 The typical behavior of chromosomes in meiosis is that homologous pairs synapse, recombine and then separate at anaphase I. At anaphase II, sister chromatids separate.
James A. Birchler, Fangpu eHan
doaj +1 more source
Toxins, 2022 Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa +6 more
doaj +1 more source
Chromosome Organization in Early Meiotic Prophase
Frontiers in Cell and Developmental Biology, 2021 One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
doaj +1 more source
Pushing the (nuclear) envelope into meiosis. [PDF]
, 2013 A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core +1 more source
Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. [PDF]
PLoS Genetics, 2013 Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereafter, in
Uddipta Biswas +6 more
doaj +1 more source
TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]
, 2015 The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi +3 more
core +1 more source
Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration
Frontiers in Neuroscience, 2018 Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity.
María J. Pérez +5 more
doaj +1 more source
Principles of meiotic chromosome assembly revealed in S. cerevisiae [PDF]
, 2019 During meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear.
A Goloborodko +69 more
core +2 more sources