Results 241 to 250 of about 326,223 (328)

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways. [PDF]

Mol Neurodegener
Kirsebom BE, Nilsson J, Vromen E, Arnesen PM, Bjørnerud A, Brinkmalm A, Bråthen G, Grøntvedt GR, Jarholm J, Nordengen K, Pålhaugen L, Selnes P, Siafarikas N, Skogseth RE, Tecelão S, Waterloo K, You P, Zetterberg H, Aarsland D, Tijms B, Visser PJ, Blennow K, Fladby T.   +22 more
europepmc   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Artificial Neuron Based on Electrical Anisotropy from WSe2 Field Effect Transistors

Advanced Science, EarlyView.
An artificial neuron was realized based on the anisotropic mobility of WSe2. Dendritic and axon‐multisynaptic performance of a neuron was achieved with optical and voltage pulses. Recognition accuracy of handwritten digits was obtained to 97% based on the synaptic weight of an artificial neuron.
Qi Sun, Ping Chen, Kun Lv, Chuanwen Chen, Jinsheng Zhu, Zhiling Chen, Yaxian Lu, Ni Zhang, Zongqian Tan, Tao Lin, Caofeng Pan   +10 more
wiley   +1 more source

Psychedelics Reverse the Polarity of Long-Term Synaptic Plasticity in Cortical-Projecting Claustrum Neurons. [PDF]

eNeuro
Anderson TL, Asadipooya A, Ortinski PI.
europepmc   +1 more source

Circadian synaptic plasticity in the mouse barrel cortex

, 2013
Małgorzata Jasińska, A. Grzegorczyk, Ewa Jasek-Gajda, Jan A. Litwin, Małgorzata Kossut, G Barbacka-Surowiak, Elżbieta Pyza   +6 more
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Interactions between long- and short-term synaptic plasticity transform temporal neural representations into spatial. [PDF]

Proc Natl Acad Sci U S A
Yu Q, Tsodyks M, Sompolinsky H, Schmitz D, Gütig R.   +4 more
europepmc   +1 more source

Faculty Opinions recommendation of Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerization.

, 2019
Eamonn J. Dickson
openalex   +2 more sources