Results 301 to 310 of about 555,224 (393)

Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease. [PDF]

Alzheimers Dement
Mecca AP, Ashton NJ, Chen MK, O'Dell RS, Toyonaga T, Zhao W, Young JJ, Salardini E, Bates KA, Ra J, Goodcase S, Silva-Rudberg JA, Nabulsi NB, Brinkmalm A, Kvartsberg H, Schöll M, Nilsson J, Arnsten AFT, Huang Y, Hansson O, Zetterberg H, Carson RE, Blennow K, van Dyck CH.   +23 more
europepmc   +1 more source

Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley   +1 more source

CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms. [PDF]

J Cell Biol
Khosrozadeh A, Seeger R, Witz G, Radecke J, Sørensen JB, Zuber B.   +5 more
europepmc   +1 more source

Establishment of a novel lipid and content mixing assay to resolve the regulatory effect of Munc18-1 and CpxII on SNARE-mediated membrane fusion of reconstituted VAMP2/Syt1 SUVs and isolated rat brain synaptic vesicles.

, 2015
Maximilian Pfau
openalex   +1 more source

Enhancing Neural Stem Cell Proliferation Using Polyurethane/CNT Scaffolds Functionalized With Liposomal Hesperidin for Neural Tissue Engineering

Nano Select, EarlyView.
A multifunctional electrospun scaffold combining polyurethane, carbon nanotubes, and liposomal hesperidin supports neural stem cell survival, adhesion, and expansion. This platform enhances conductivity, mechanical strength, and hydrophilicity while mimicking the native neural environment.
Arman Abroumand Gholami, Amir Mahdi Molavi, Meshkat Omrannezhad, Tahere Mokhtari, Shokoufeh Rahmani, Payam Moharreri, Fatemeh Gheybi, Fatemeh Tahmasebi, Hamideh Babaloo   +8 more
wiley   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. [PDF]

J Physiol
Afuwape OAT, Chanaday NL, Kasap M, Monteggia LM, Kavalali ET.   +4 more
europepmc   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Rasopathy-Associated Mutation Ptpn11^D61Y has Age-Dependent Effect on Synaptic Vesicle Recycling. [PDF]

Cell Mol Neurobiol
Guhathakurta D, Selzam F, Petrušková A, Weiss EM, Akdaş EY, Montenegro-Venegas C, Zenker M, Fejtová A.   +7 more
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source