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The synaptic vesicle proteome [PDF]

open access: yesJournal of Neurochemistry, 2007
AbstractSynaptic vesicles are key organelles in neurotransmission. Vesicle integral or membrane‐associated proteins mediate the various functions the organelle fulfills during its life cycle. These include organelle transport, interaction with the nerve terminal cytoskeleton, uptake and storage of low molecular weight constituents, and the regulated ...
Jacqueline Burr
exaly   +4 more sources

Synaptic vesicle pools: an update [PDF]

open access: yesFrontiers in Synaptic Neuroscience, 2010
During the last few decades synaptic vesicles have been assigned to a variety of functional and morphological classes or "pools". We have argued in the past (Rizzoli and Betz, 2005) that synaptic activity in several preparations is accounted for by the function of three vesicle pools: the readily releasable pool (docked at active zones and ready to go ...
Silvio O Rizzoli
exaly   +5 more sources

Synaptic Vesicle Biogenesis [PDF]

open access: possibleAnnual Review of Cell and Developmental Biology, 1999
▪ Abstract  Synaptic vesicles, which have been a paradigm for the fusion of a vesicle with its target membrane, also serve as a model for understanding the formation of a vesicle from its donor membrane. Synaptic vesicles, which are formed and recycled at the periphery of the neuron, contain a highly restricted set of neuronal proteins.
Matthew J. Hannah   +2 more
openaire   +2 more sources
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Synaptic vesicles

Biochemical Pharmacology, 1970
Abstract Isolated synaptosomes from guinea pig brain homogenates incorporated choline- 14 C when incubated either in a medium with an external energy source or in one containing only Tris buffer. The incorporation was divisible into three fractions: total, TCA-insoluble, and chloroform-soluble.
Brian A. Hemsworth, H B Bosmann
openaire   +3 more sources

Formation of synaptic vesicles

Current Opinion in Cell Biology, 1994
Synaptic vesicles (SVs) are specialized secretory organelles used for the fast and focal signaling between nerve cells. They are small and homogeneous in size (50 nm), and contain non-peptide neurotransmitters such as glutamate, gamma-aminobutyric acid (GABA) and acetylcholine. The exocytosis of SVs occurs at low rates in resting nerve terminals and is
O Mundigl, Pietro De Camilli
openaire   +3 more sources

Synaptic Vesicles and Exocytosis [PDF]

open access: possibleAnnual Review of Neuroscience, 1994
Neurons transmit information by releasing neurotransmitters from presynaptic nerve endings, In the resting stage , transmitters are stored in small organelles of uniform size and shape , the synaptic vesicles . When an action potential arrives in the nerve terminal , the membrane depolarizes and voltage-gated Ca2+ channels open .
Reinhard Jahn, Thomas C. Südhof
openaire   +2 more sources

Isolation of Synaptic Vesicles

Current Protocols in Cell Biology, 2004
AbstractSynaptic vesicles are the most abundant secretory organelle in eukaryotic neural cells. Synaptic vesicles are physically distinct from other membrane‐bound organelles because they are small, spherical, and highly uniform in size with a diameter of about 40 nm.
Gloria Salazar   +2 more
openaire   +3 more sources

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