Results 311 to 320 of about 107,361 (347)
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Biogenesis of synaptic vesicles
Journal of Cell Science, 1993ABSTRACT The basic endosomal recycling pathway can be modified to generate transcytotic vesicles, storage vesicles and synaptic vesicles. Sorting into synaptic vesicles requires specialized sorting information not present in the transcytotic and storage vesicle proteins.
Regis B. Kelly+5 more
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Synaptic Vesicles in the Cochlea
Acta Oto-Laryngologica, 1974The cochlea is innervated by afferent, efferent and sympathetic neurons. The afferent synapses and the efferent and sympathetic nerve terminals contain transmitter substances within their synaptic vesicles. These transmitters are likely to be chemically different in each of the three cochlear nerve populations.
Ove Densert, A Flock, E Borg
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Nature Reviews Neuroscience, 2005
Communication between cells reaches its highest degree of specialization at chemical synapses. Some synapses talk in a 'whisper'; others 'shout'. The 'louder' the synapse, the more synaptic vesicles are needed to maintain effective transmission, ranging from a few hundred (whisperers) to nearly a million (shouters).
William J. Betz, Silvio O. Rizzoli
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Communication between cells reaches its highest degree of specialization at chemical synapses. Some synapses talk in a 'whisper'; others 'shout'. The 'louder' the synapse, the more synaptic vesicles are needed to maintain effective transmission, ranging from a few hundred (whisperers) to nearly a million (shouters).
William J. Betz, Silvio O. Rizzoli
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‘Synaptic Vesicles’ in the Neurohypophysis
Nature, 1960ELECTRON microscope studies of the neurohypophysis have shown that the terminal branches of the hypothalamo-hypophysial tract fibres contain, in addition to mitochondria, vesicles or granules of two kinds distinguished by their size1,2. The larger inclusions each have a diameter of the order of 100–300 mµ, (1000–3000 A.), and are thought to represent ...
R. L. Holmes, Francis Knowles
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Annual Review of Physiology, 1998
▪ Abstract The ins and outs of the synaptic vesicle cycle are being examined in increasing detail with diverse investigative tools in a variety of cell types, particularly those with large granules. The cycle begins with the opening of a fusion pore that connects the vesicle lumen to the extracellular fluid.
Joseph K. Angleson, William J. Betz
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▪ Abstract The ins and outs of the synaptic vesicle cycle are being examined in increasing detail with diverse investigative tools in a variety of cell types, particularly those with large granules. The cycle begins with the opening of a fusion pore that connects the vesicle lumen to the extracellular fluid.
Joseph K. Angleson, William J. Betz
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Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function
Science, 1993Complex brain functions, such as learning and memory, are believed to involve changes in the efficiency of communication between nerve cells. Therefore, the elucidation of the molecular mechanisms that regulate synaptic transmission, the process of intercellular communication, is an essential step toward understanding nervous system function.
GREENGARD P.+3 more
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Annual Review of Neuroscience, 2004
▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release, synaptic vesicles undergo a trafficking cycle. The focal point of the vesicle cycle is Ca2+-triggered exocytosis that is followed by different routes of endocytosis and ...
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▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release, synaptic vesicles undergo a trafficking cycle. The focal point of the vesicle cycle is Ca2+-triggered exocytosis that is followed by different routes of endocytosis and ...
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1984
Synaptic vesicles are the characteristic organelles of the presynaptic nerve terminals of chemical synapses (i.e., those utilizing the release of a specific chemical transmitter substance to bring about synaptic transmission). They are normally 45–50 nm in diameter and must be among the most homogeneous and uniform lipoprotein membrane organelles known.
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Synaptic vesicles are the characteristic organelles of the presynaptic nerve terminals of chemical synapses (i.e., those utilizing the release of a specific chemical transmitter substance to bring about synaptic transmission). They are normally 45–50 nm in diameter and must be among the most homogeneous and uniform lipoprotein membrane organelles known.
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Mechanisms of Synaptic Vesicle Exocytosis
Annual Review of Cell and Developmental Biology, 2000▪ Abstract Chemical synaptic transmission serves as the main form of cell to cell communication in the nervous system. Neurotransmitter release occurs through the process of regulated exocytosis, in which a synaptic vesicle releases its contents in response to an increase in calcium.
Richard H. Scheller, Richard C. Lin
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ELECTROPHYSIOLOGY OF SYNAPTIC VESICLE CYCLING
Annual Review of Physiology, 1999▪ Abstract Patch-clamp capacitance measurements can monitor in real time the kinetics of exocytosis and endocytosis in living cells. We review the application of this technique to the giant presynaptic terminals of goldfish bipolar cells. These terminals secrete glutamate via the fusion of small, clear-core vesicles at specialized, active zones of ...
Henrique von Gersdorff, Gary Matthews
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