Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. [PDF]
Held RG, Liang J, Brunger AT.
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Co-packaging of opposing neurotransmitters in individual synaptic vesicles in the central nervous system. [PDF]
Kim S+4 more
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Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li+9 more
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Beyond the MUN domain, Munc13 controls priming and depriming of synaptic vesicles. [PDF]
Leitz J+7 more
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Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice. [PDF]
Lian Li+9 more
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Organoid‐tissue extracellular vesicles
Abstract Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological state of the tissue microenvironment.
Han Liu+6 more
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5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder. [PDF]
Chang P+8 more
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Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles. [PDF]
Cristofari P+17 more
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Amphiphysin, a novel protein associated with synaptic vesicles.
Beate Lichte+3 more
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