Results 251 to 260 of about 549,591 (370)

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

SV2B defines a subpopulation of synaptic vesicles. [PDF]

J Mol Cell Biol
Paulussen I, Beckert H, Musial TF, Gschossmann LJ, Wolf J, Schmitt M, Clasadonte J, Mairet-Coello G, Wolff C, Schoch S, Dietrich D.   +10 more
europepmc   +1 more source

Neural Synaptic Vesicle Autoimmunity Following Occupational Exposure to Aerosolized Porcine Neural Tissue: Etiologic and Immunopathogenic Insights into Autoimmune Inflammatory Polyradiculoneuropathy

Shannon R. Hinson, Pranjal Gupta, Naveen Kumar Paramasivan, P. James B. Dyck, Vanda A. Lennon, Daniel H. Lachance, Andrew Knight, Mohamed Rezk, Carley Karsten, Reghann G. LaFrance‐Corey, Nathan P. Staff, Sybil Hrstka, Joseph C. Wu, Christopher J. Klein, Αναστασία Ζεκερίδου, Andrew McKeon, Sean J Pittock, Cinta Lleixà, Luís Querol, Surendra Dasari, John R. Mills, Divyanshu Dubey   +21 more
openalex   +1 more source

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short-term plasticity. [PDF]

J Physiol
Lin KH, Ranjan M, Lipstein N, Brose N, Neher E, Taschenberger H.   +5 more
europepmc   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca²⁺ ATPase to promote recycling of synaptic vesicles. [PDF]

Elife
Seidenthal M, Redzovic J, Liewald JF, Rentsch D, Shapiguzov S, Schuh N, Rosenkranz N, Eimer S, Gottschalk A.   +8 more
europepmc   +1 more source

Working Memory Impairment in Calcineurin Knock-out Mice Is Associated with Alterations in Synaptic Vesicle Cycling and Disruption of High-Frequency Synaptic and Network Activity in Prefrontal Cortex [PDF]

, 2013
Jeffrey R. Cottrell, Jonathan M. Levenson, Sung Hyun Kim, Helen E. Gibson, Kara Richardson, Michael Sivula, Bing Li, Crystle J. Ashford, K. A. Heindl, Ryan J. Babcock, David M. Rose, Chris M. Hempel, Kjesten A. Wiig, Pascal Laeng, Michael E. Levin, Timothy A. Ryan, David J. Gerber   +16 more
openalex   +1 more source

A novel synaptopathy‐defective synaptic vesicle protein trafficking in the mutant CHMP2B mouse model of frontotemporal dementia

, 2021
Emma L. Clayton, Katherine Bonnycastle, Adrian M. Isaacs, Michael A. Cousin, Stéphanie Schorge   +4 more
openalex   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source