Miniature endplate current rise times less than 100 microseconds from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle. [PDF]
Joel R. Stiles+4 more
openalex +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles. [PDF]
Park D+6 more
europepmc +1 more source
Spontaneously Recycling Synaptic Vesicles Constitute Readily Releasable Vesicles in Intact Neuromuscular Synapses. [PDF]
Egashira Y, Kumade A, Ojida A, Ono F.
europepmc +1 more source
Molecular Mechanisms in Synaptic Vesicle Endocytosis and Recycling [PDF]
Pietro De Camilli, Kohji Takei
openalex +1 more source
Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2
Abstract Background Bridge‐like lipid transfer proteins (BLTPs) mediate bulk lipid transport at membrane contact sites. Mutations in BLTPs are linked to both early‐onset neurodevelopmental and later‐onset neurodegenerative diseases, including movement disorders.
Sarah D. Neuman+4 more
wiley +1 more source
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles. [PDF]
Céspedes PF+25 more
europepmc +1 more source
Continuous Vesicle Cycling in the Synaptic Terminal of Retinal Bipolar Cells [PDF]
Leon Lagnado, Ana Gomis, Christy Job
openalex +1 more source
Annette Denker+4 more
semanticscholar +1 more source
Abstract Background Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural responses could shed light on circuit pathophysiology and inform novel approaches to neuromodulation therapies.
Sarah Brinkerhoff+7 more
wiley +1 more source