Results 101 to 110 of about 6,519,238 (204)
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. [PDF]
PLoS ONE, 2014 Synaptonemal complex protein 3 (SCP3), a member of Cor1 family, is up-regulated in various cancer cells; however, its oncogenic potential and clinical significance has not yet been characterized.
Hanbyoul Cho +8 more
doaj +1 more source
Molecular structure of human synaptonemal complex protein SYCE1
Chromosoma, 2019 The reduction in chromosome number during meiosis is essential for the production of haploid germ cells and thereby fertility. To achieve this, homologous chromosomes are first synapsed together by a protein assembly, the synaptonemal complex (SC), which
O. Dunne, O. Davies
semanticscholar +1 more source
RECQ4 restricts non‐interfering crossover formation to fine‐tune meiotic recombination rates in rice
Plant Biotechnology Journal, Volume 23, Issue 9, Page 3760-3769, September 2025.Summary Crop breeding fundamentally depends on meiotic crossovers (COs) to reshuffle genetic material and integrate favourable alleles into elite cultivars. Recombination frequency is of paramount importance in this process. Higher recombination rates enhance the probability of breaking linkage drag and generating novel allelic combinations.
Yafei Li +11 more
wiley +1 more source
The Role of Foundational Relations in the Alignment of Biomedical Ontologies [PDF]
, 2004 The Foundational Model of Anatomy (FMA) symbolically represents the structural organization of the human body from the macromolecular to the macroscopic levels, with the goal of providing a robust and consistent scheme for classifying anatomical entities
Rosse, Cornelius, Smith, Barry
core +1 more source
Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk [PDF]
, 2011 During meiosis, one round of deoxyribonucleic acid replication is followed by two rounds of nuclear division. In Saccharomyces cerevisiae, activation of the Cdc14 early anaphase release (FEAR) network is required for exit from meiosis I but does not lead
Arumugam, Prakash +5 more
core +3 more sources
Вавиловский журнал генетики и селекции, 2019 Chromosomal rearrangements can lead to the formation of new stable karyotypes, nevertheless changing the architectonics of the nucleus. The differences in locations might promote Robertsonian (Rb) translocations and encourage meiotic drive in favour of ...
V. G. Tambovtseva +5 more
doaj +1 more source
PLoS Genetics, 2018 During meiosis, the maternal and paternal homologous chromosomes must align along their entire length and recombine to achieve faithful segregation in the gametes. Meiotic recombination is accomplished through the formation of DNA double-strand breaks, a
Eva Janisiw +3 more
semanticscholar +1 more source
Molecular Ecology Resources, Volume 25, Issue 6, August 2025.ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty +6 more
wiley +1 more source
Structural analysis of the human SYCE2–TEX12 complex provides molecular insights into synaptonemal complex assembly [PDF]
Open Biology, 2012 The successful completion of meiosis is essential for all sexually reproducing organisms. The synaptonemal complex (SC) is a large proteinaceous structure that holds together homologous chromosomes during meiosis, providing the structural framework for ...
Owen R. Davies +2 more
doaj +1 more source
Cell Proliferation, Volume 58, Issue 7, July 2025.PDHA2, a testis‐specific subunit of pyruvate dehydrogenase, is required for the conversion of pyruvate to acetyl‐CoA. Its absence results in decreased acetyl‐CoA and precursors for metabolites and energy during spermatogenesis. This results in decreased histone acetylation, defective chromosome structure and moderately reduced crossovers, ultimately ...
Guoqiang Wang +9 more
wiley +1 more source