Results 101 to 110 of about 6,599,798 (249)
Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. [PDF]
PLoS Genetics, 2012 The intimate synapsis of homologous chromosome pairs (homologs) by synaptonemal complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and homologous recombination are interdependent: recombination promotes SC formation and SCs ...
Huanyu Qiao +5 more
doaj +1 more source
The Role of Foundational Relations in the Alignment of Biomedical Ontologies [PDF]
, 2004 The Foundational Model of Anatomy (FMA) symbolically represents the structural organization of the human body from the macromolecular to the macroscopic levels, with the goal of providing a robust and consistent scheme for classifying anatomical entities
Rosse, Cornelius, Smith, Barry
core +1 more source
TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]
, 2015 The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi +3 more
core +1 more source
Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica
New Phytologist, Volume 249, Issue 1, Page 524-538, January 2026.Summary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Robin Burns +6 more
wiley +1 more source
PLoS Genetics, 2019 The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
Laura Gómez-H +11 more
doaj +1 more source
Frontiers in Plant Science, 2018 The repair of SPO11-dependent double-strand breaks (DSBs) by homologous recombination (HR) ensures the correct segregation of homologous chromosomes. In yeast and human, RAD17 is involved in DNA damage checkpoint control and DSB repair.
Qing Hu +10 more
doaj +1 more source
Mixing and Matching Chromosomes during Female Meiosis
Cells, 2020 Meiosis is a key event in the manufacturing of an oocyte. During this process, the oocyte creates a set of unique chromosomes by recombining paternal and maternal copies of homologous chromosomes, and by eliminating one set of chromosomes to become ...
Thomas Rubin +2 more
doaj +1 more source
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. [PDF]
PLoS ONE, 2014 Synaptonemal complex protein 3 (SCP3), a member of Cor1 family, is up-regulated in various cancer cells; however, its oncogenic potential and clinical significance has not yet been characterized.
Hanbyoul Cho +8 more
doaj +1 more source
Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk [PDF]
, 2011 During meiosis, one round of deoxyribonucleic acid replication is followed by two rounds of nuclear division. In Saccharomyces cerevisiae, activation of the Cdc14 early anaphase release (FEAR) network is required for exit from meiosis I but does not lead
Arumugam, Prakash +5 more
core +3 more sources
Eukaryogenesis From FECA to LECA: Radical Steps Along the Way
BioEssays, Volume 47, Issue 11, November 2025.How did the last eukaryotic common ancestor (LECA) population evolve? Recent evidence shows an Asgard archaeon‐like organism acquiring a bacterium, the future mitochondrion, going from symbiosis to endosymbiosis. I postulate that almost all salient LECA characteristics could have resulted from the ensuing enhanced ATP generation and internal reactive ...
Dave Speijer
wiley +1 more source