Results 111 to 120 of about 6,519,238 (204)

Ultrastructure and Dynamics of Synaptonemal Complex Components During Meiotic Pairing and Synapsis of Standard (A) and Accessory (B) Rye Chromosomes

Frontiers in Plant Science, 2019
During prophase I a meiosis-specific proteinaceous tripartite structure, the synaptonemal complex (SC), forms a scaffold to connect homologous chromosomes along their lengths.
Susann Hesse, Mateusz Zelkowski, E. Mikhailova, C. J. Keijzer, A. Houben, V. Schubert   +5 more
semanticscholar   +1 more source

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

Aging Cell, Volume 24, Issue 6, June 2025.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang   +9 more
wiley   +1 more source

CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase [PDF]

, 2015
In most organisms, telomeres attach to the nuclear envelope at the onset of meiosis to promote the crucial processes of pairing, recombination and synapsis during prophase I.
Alsheimer, M., Benavente, R., Berenguer, I., Gómez, R., Ortega, S., Santamaría, Daniel F., Suja Sánchez, José Ángel, Symonds, C.E., Viera, A.   +8 more
core   +2 more sources

New method for visualization of C-heterochromatin in synaptonemal complex spreads

Comparative Cytogenetics, 2013
DAPI staining of the metaphase chromosomes pretreated with barium hydroxide generates a C-like banding pattern. In this work a protocol for visualizing similar pattern at the synaptonemal complex (SC) spreads after immunostaining is suggested.
Artem Lisachov
doaj   +1 more source

Molecular characterization and expression analysis of SYCP1 and SYCP3 in hybrid fish derived from Megalobrama amblycephala × Culter alburnus

Journal of the World Aquaculture Society, Volume 56, Issue 3, June 2025.
Abstract SYCP1 and SYCP3 are essential testis‐specific genes for centromere pairing during meiosis, as well as for spermatogenesis and fertility in male germ cells. However, it is still unclear regarding the expression patterns in the fertile reciprocal hybrid offspring of Megalobrama amblycephala (blunt snout bream, BSB, 2n = 48) × Culter alburnus ...
Jia Xu, Yuandong Sun, Chang Wu, Xiaojuan Cui, Yujing Li, Zhongwei Hua, Yifei Zhang   +6 more
wiley   +1 more source

Meiotic double strand breaks repair in sexually reproducing eukaryotes: We are not all equal. [PDF]

, 2012
The defining event of meiosis is prophase-I, during which the maternal and paternal chromosome find each other in the nucleus, pair, and align in a process called “synapses of the homologues”. Their faithful segregation during the first meiotic division (
Barchi, M, La Volpe, A
core   +1 more source

Cytomixis doesn’t induce obvious changes in chromatin modifications and programmed cell death in tobacco male meiocytes

Frontiers in Plant Science, 2015
Cytomixis is a poorly studied process of nuclear migration between plant cells. It is so far unknown what drives cytomixis and what is the functional state of the chromatin migrating between cells.
Sergey eMursalimov, Natalya ePermyakova, Elena eDeineko, Andreas eHouben, Dmitri eDemidov   +4 more
doaj   +1 more source

Programming for Meiotic Competence in Mouse Male Germ Cells is Established at the Perinatal Precursor Stage of Development

Molecular Reproduction and Development, Volume 92, Issue 5, May 2025.
ABSTRACT Meiosis is a fundamental aspect of gametogenesis, but how and when the programming is established in germ cells during development is unknown. In the mammalian male germline, mitotic differentiating spermatogonia with the competence for meiotic divisions arise from an undifferentiated pool of spermatogonia that are descended from ...
Qi‐En Yang, Mingyao Yang, Melissa J. Oatley, Jon M. Oatley   +3 more
wiley   +1 more source

Synaptic configuration of quadrivalents and their association with the XY bivalent in spermatocytes of Robertsonian heterozygotes of Mus domesticus

Biological Research, 2017
Background The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains and consequently is prone to modification by chromosomal rearrangements.
Soledad Berríos, Raúl Fernández-Donoso, Eliana Ayarza   +2 more
doaj   +1 more source

SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice

Nucleic Acids Research, 2019
Meiosis is a specialized cell division for producing haploid gametes from diploid germ cells. During meiosis, synaptonemal complex (SC) mediates the alignment of homologs and plays essential roles in homologous recombination and therefore in promoting ...
Hongbin Liu, Tao Huang, Mengjing Li, Miao Li, Chuanxin Zhang, Jing Jiang, Xiaochen Yu, Yingying Yin, Fan Zhang, Gang Lu, Mengcheng Luo, Liang-Ran Zhang, Jinsong Li, Kui Liu, Zi-Jiang Chen   +14 more
semanticscholar   +1 more source