Results 51 to 60 of about 6,967 (166)

Meiotic Chromosome Dynamics in Zebrafish

Frontiers in Cell and Developmental Biology, 2021
Recent studies in zebrafish have revealed key features of meiotic chromosome dynamics, including clustering of telomeres in the bouquet configuration, biogenesis of chromosome axis structures, and the assembly and disassembly of the synaptonemal complex ...
Yukiko Imai, Ivan Olaya, Ivan Olaya, Noriyoshi Sakai, Noriyoshi Sakai, Sean M. Burgess   +5 more
doaj   +1 more source

Somatic genome‐doubling is the most parsimonious route to allopolyploidy

New Phytologist, Volume 250, Issue 5, Page 2845-2851, June 2026.
Summary The origin of a polyploid can hinge on a single errant cell division, a mistake in the cell cycle that leads to genome‐doubling and re‐writes the rules of chromosome pairing and segregation. In plants, the evolutionary significance of these errors is magnified by lack of an early sequestered germline, meaning somatic mutations can be heritable.
Robin Burns, Alison Dawn Scott, Polina Yu Novikova   +2 more
wiley   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, Volume 13, Issue 22, 17 April 2026.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source

BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis

Cell Proliferation, Volume 59, Issue 4, April 2026.
This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li, Lingya Mao, Boyuan Liang, Longxin Xie, Wenpei Xiang, Kehkooi Kee   +5 more
wiley   +1 more source

Review of expansion microscopy combined with advanced imaging modalities

Journal of Microscopy, Volume 301, Issue 3, Page 335-354, March 2026.
Abstract Expansion microscopy (ExM) is a powerful high‐resolution imaging technique that enhances the spatial resolution of conventional light microscopy by physically enlarging biological specimens by embedding and cross‐linking them in a swellable polymer network.
Natalie Woo, Claire M. Brown
wiley   +1 more source

Genomic introgressions from wild relatives in the wheat genome alter meiotic dynamics in inter‐varietal hybrids

The Plant Journal, Volume 125, Issue 5, March 2026.
SUMMARY The use of wild relatives to introduce original diversity in the genome of bread wheat (Triticum aestivum L.) is an interesting approach to face the challenges of sustainable agriculture and the impact of climate change on wheat production. However, the influence of these wild‐species introgressions on meiosis in inter‐varietal wheat hybrids ...
Luxi Yan, Floriane Chéron, Isabelle Nadaud, Ming Hao, Dengcai Liu, Pierre Sourdille   +5 more
wiley   +1 more source

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

PLoS Genetics, 2019
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
Laura Gómez-H, Natalia Felipe-Medina, Yazmine B Condezo, Rodrigo Garcia-Valiente, Isabel Ramos, José Angel Suja, José Luis Barbero, Ignasi Roig, Manuel Sánchez-Martín, Dirk G de Rooij, Elena Llano, Alberto M Pendas   +11 more
doaj   +1 more source

Mixing and Matching Chromosomes during Female Meiosis

Cells, 2020
Meiosis is a key event in the manufacturing of an oocyte. During this process, the oocyte creates a set of unique chromosomes by recombining paternal and maternal copies of homologous chromosomes, and by eliminating one set of chromosomes to become ...
Thomas Rubin, Nicolas Macaisne, Jean-René Huynh   +2 more
doaj   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, Volume 13, Issue 9, 13 February 2026.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

Testicular Morphology and Spermatogenesis in Potamotrygon motoro: Insights Into Reproduction of Freshwater Stingrays

Journal of Morphology, Volume 287, Issue 2, February 2026.
Electron microscopy of Potamotrygon motoro spermatozoa. a – Illustration of a schematic sperm cell depicting the helical head, intermediate piece (midpiece), and flagellum. b ‐ Helical heads (Hh) of spermatozoa inserted into the cytoplasm of Sertoli cells (S) through openings in the plasma membrane. Scales: 10 μm.
Maria Luiza Ribeiro Delgado, Patricia Postingel Quirino, Luciane Gomes‐Silva, Viktoriya Dzyuba, Borys Dzyuba, Alexandre Ninhaus‐Silveira, Rosicleire Veríssimo‐Silveira   +6 more
wiley   +1 more source