Results 41 to 50 of about 13,512 (241)

A molecular cell biology toolkit for the study of meiosis in the silkworm Bombyx mori

open access: yesG3: Genes, Genomes, Genetics, 2023
Meiosis is usually described as 4 essential and sequential processes: (1) homolog pairing; (2) synapsis, mediated by the synaptonemal complex; (3) crossing over; and (4) segregation.
Youbin Xiang   +9 more
doaj   +1 more source

A BIRD´S-EYE VIEW OF CHROMOSOMES DURING MEIOTIC PROPHASE I [PDF]

open access: yesBAG. Journal of Basic and Applied Genetics, 2022
The present review aims to summarize the research carried out in relation to meiosis in birds, especially by observing the protein axes of the chromosomes in prophase I of meiosis. This line of research, initially developed in Argentina, has provided key
Pigozzi M.I.
doaj   +1 more source

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]

open access: yes, 2019
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema   +10 more
core   +4 more sources

Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes.

open access: yesPLoS Genetics, 2020
Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures.
Kazumasa Takemoto   +6 more
doaj   +1 more source

Application of advanced fluorescence microscopy to the structure of meiotic chromosomes [PDF]

open access: yes, 2013
Chromosomes undergoing meiosis are defined by a macromolecular protein assembly called the synaptonemal complex which holds homologs together and carries out important meiotic functions.
Carlton, Peter M.
core   +1 more source

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

open access: yes, 2020
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U.   +6 more
core   +1 more source

Evidence that MEK1 positively promotes interhomologue double-strand break repair [PDF]

open access: yes, 2010
During meiosis there is an imperative to create sufficient crossovers for homologue segregation. This can be achieved during repair of programmed DNA double-strand breaks (DSBs), which are biased towards using a homologue rather than sister chromatid as ...
Bishop-Bailey, A   +5 more
core   +1 more source

Somatic role of SYCE2: an insulator that dissociates HP1α from H3K9me3 and potentiates DNA repair

open access: yesLife Science Alliance, 2018
This study reveals that the synaptonemal complex protein SYCE2 potentiates ataxia telangiectasia mutated–mediated DNA double-strand break repair by dissociating HP1α from trimethylated histone H3 lysine 9 in somatic cells.
Noriko Hosoya   +2 more
doaj   +1 more source

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination [PDF]

open access: yes, 2015
In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism.
Alexandra-Styliani Kalantzi   +66 more
core   +3 more sources

Synaptonemal Complexities and Commonalities [PDF]

open access: yesMolecular Cell, 2003
Formation of synaptonemal complex and high levels of homologous recombination are the hallmarks of meiotic prophase. The relationship between these two processes has been the subject of intense study for nearly 50 years. Recent findings highlight the differences and commonalities of this relationship in different species.
openaire   +2 more sources

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