Results 61 to 70 of about 284,832 (240)
An atomic force microscopical study of the synaptonemal complex [PDF]
The chromosomal structure which is specific for meiosis, the synaptonemal complex (SC), plays a major role in chromosome pairing and the recombination of genetic material. The SC was studied using atomic force microscopy (AFM). The results of this study confirm the results of light and electron microscopic studies of the SC.
Putman, C.A.J.+6 more
openaire +2 more sources
New method for visualization of C-heterochromatin in synaptonemal complex spreads
DAPI staining of the metaphase chromosomes pretreated with barium hydroxide generates a C-like banding pattern. In this work a protocol for visualizing similar pattern at the synaptonemal complex (SC) spreads after immunostaining is suggested.
Artem Lisachov
doaj +1 more source
Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. [PDF]
The intimate synapsis of homologous chromosome pairs (homologs) by synaptonemal complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and homologous recombination are interdependent: recombination promotes SC formation and SCs ...
Huanyu Qiao+5 more
doaj +1 more source
Higher analogs of simplicial and combinatorial complexity [PDF]
We introduce higher simplicial complexity of a simplicial complex $K$ and higher combinatorial complexity of a finite space $P$ (i.e. $P$ is a finite poset). We relate higher simplicial complexity with higher topological complexity of $|K|$ and higher combinatorial complexity with higher simplicial complexity of the order complex of $P$.
arxiv
METTL16 predominantly controls the expression of critical meiotic genes essential for DSB formation and recombination in early meiotic spermatocytes and is involved in the expansion of DNA damage response (DDR) factors and epigenetic modifications in the XY body for the establishment and maintenance of meiotic sex chromosome inactivation (MSCI) in ...
Lisha Yin+16 more
wiley +1 more source
Protein-protein interactions in the synaptonemal complex. [PDF]
In mammalian systems, an approximately M(r) 30,000 Cor1 protein has been identified as a major component of the meiotic prophase chromosome cores, and a M(r) 125,000 Syn1 protein is present between homologue cores where they are synapsed and form the synaptonemal complex (SC). Immunolocalization of these proteins during meiosis suggests possible homo-
M S Park+4 more
openaire +3 more sources
The repair of SPO11-dependent double-strand breaks (DSBs) by homologous recombination (HR) ensures the correct segregation of homologous chromosomes. In yeast and human, RAD17 is involved in DNA damage checkpoint control and DSB repair.
Qing Hu+10 more
doaj +1 more source
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. [PDF]
Synaptonemal complex protein 3 (SCP3), a member of Cor1 family, is up-regulated in various cancer cells; however, its oncogenic potential and clinical significance has not yet been characterized.
Hanbyoul Cho+8 more
doaj +1 more source
On a special class of complex tori [PDF]
We investigate which complex tori admits complex Lie subgroups whose closure is not complex.
arxiv
Prenatal exposure to silicon dioxide nanoparticles (SiO2 NPs) caused subfertility in female offspring, reducing ovulation, ovarian reserve, and litter size, while male offspring remained unaffected. Mechanistic analysis revealed disrupted meiotic recombination and increased oocyte apoptosis in females. COOH‐functionalized SiO2 NPs showed minimal impact
Min Lei+15 more
wiley +1 more source