Results 71 to 80 of about 284,832 (240)
Sexual dimorphism in the width of the mouse synaptonemal complex [PDF]
ABSTRACT Sexual dimorphism has been used to describe morphological differences between the sexes, but can be extended to any biologically related process that varies between males and females. The synaptonemal complex (SC) is a tripartite structure that connects homologous chromosomes in meiosis.
Ana Agostinho+6 more
openaire +3 more sources
Graphical abstract showing the mechanism by which dTECM‐SLC‐based therapy ameliorates testicular LC dysfunction. Local injection of dTECM‐SLC into the testicular interstitium. dTECM creates a favorable microenvironment for SLC proliferation and differentiation.
Ani Chi+4 more
wiley +1 more source
Chromosomal rearrangements can lead to the formation of new stable karyotypes, nevertheless changing the architectonics of the nucleus. The differences in locations might promote Robertsonian (Rb) translocations and encourage meiotic drive in favour of ...
V. G. Tambovtseva+5 more
doaj +1 more source
Structural analysis of the human SYCE2–TEX12 complex provides molecular insights into synaptonemal complex assembly [PDF]
The successful completion of meiosis is essential for all sexually reproducing organisms. The synaptonemal complex (SC) is a large proteinaceous structure that holds together homologous chromosomes during meiosis, providing the structural framework for ...
Owen R. Davies+2 more
doaj +1 more source
We introduce decomposition complexes of posets, which generalize order complexes. The main advantage of our construction is that decomposition complexes are closed under taking products. Other special instances of this theory include nested set complexes as well as Bergman complexes.
arxiv
Complex Intersection Bodies [PDF]
We introduce complex intersection bodies and show that their properties and applications are similar to those of their real counterparts. In particular, we generalize Busemann's theorem to the complex case by proving that complex intersection bodies of symmetric complex convex bodies are also convex.
arxiv +1 more source
TRIP13: A promising cancer immunotherapy target
Thyroid hormone receptor interactor 13 (TRIP13) inhibition presents a promising avenue for immunotherapy against tumors. Administration of DCZ0415 to immunocompetent myeloma models resulted in an upregulation of immune cells infiltrated in the tumor microenvironment, suggesting the immunotherapeutic potential of TRIP13 inhibition.
Shengnan Jing+4 more
wiley +1 more source
Mixing and Matching Chromosomes during Female Meiosis
Meiosis is a key event in the manufacturing of an oocyte. During this process, the oocyte creates a set of unique chromosomes by recombining paternal and maternal copies of homologous chromosomes, and by eliminating one set of chromosomes to become ...
Thomas Rubin+2 more
doaj +1 more source
The role and mechanism of NAT10‐mediated ac4C modification in tumor development and progression
RNA modification is a critical area of study within epigenetics, profoundly influencing the biological functions of tumors. Among these modifications, N4‐acetylcytidine (ac4C) stands out as the sole acetylation modification found in eukaryotic RNA. This modification is catalyzed by N‐acetyltransferase 10 (NAT10).
Zhuoran Gu+14 more
wiley +1 more source
Matching trees for simplicial complexes and homotopy type of devoid complexes of graphs [PDF]
We generalize some homotopy calculation techniques such as splittings and matching trees that are introduced for the computations in the case of the independence complexes of graphs to arbitrary simplicial complexes, and exemplify their efficiency on some simplicial complexes, the devoid complexes of graphs, which are simplicial complexes parametrized ...
arxiv