Results 71 to 80 of about 12,224 (202)

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

New Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr, Sybille Ursula Mittmann, Luke Ramsay, Dominika Lewandowska, Abdellah Barakate, Malcolm Macaulay, Nicola McCallum, Robbie Waugh, Isabelle Colas   +8 more
wiley   +1 more source

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

PLoS Genetics, 2019
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
Laura Gómez-H, Natalia Felipe-Medina, Yazmine B Condezo, Rodrigo Garcia-Valiente, Isabel Ramos, José Angel Suja, José Luis Barbero, Ignasi Roig, Manuel Sánchez-Martín, Dirk G de Rooij, Elena Llano, Alberto M Pendas   +11 more
doaj   +1 more source

Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes [PDF]

, 2015
Background: Different moderrn methodologies are presently available to analyze meiotic chromosomes. These methods permit investigation of the behavior of chromosomes in the normal complement and of sex and B chromosomes, two special types of chromosomes ...
Cláudio Oliveira, Cristian Araya-Jaime, Duílio de Andrade Silva, Fausto Foresti, Masakane Yamashita, Toshiharu Iwai, Érica Serrano   +6 more
core   +2 more sources

Cellular Hallmarks From Volume Electron Microscopy Reveal Developmental Progression of Plasmodium Ookinetes

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif, Marco Rheinnecker, Kolja Hildenbrand, Thanat Chookajorn, Lilian P. Dorner, Jean‐Karim Hériché, Sara Henriksson, Charlotta Funaya, Franziska Hentzschel, Linda Sandblad, Oliver Billker, Yannick Schwab, Friedrich Frischknecht   +12 more
wiley   +1 more source

OsRAD17 Is Required for Meiotic Double-Strand Break Repair and Plays a Redundant Role With OsZIP4 in Synaptonemal Complex Assembly

Frontiers in Plant Science, 2018
The repair of SPO11-dependent double-strand breaks (DSBs) by homologous recombination (HR) ensures the correct segregation of homologous chromosomes. In yeast and human, RAD17 is involved in DNA damage checkpoint control and DSB repair.
Qing Hu, Qing Hu, Chao Zhang, Chao Zhang, Zhihui Xue, Lijun Ma, Wei Liu, Yi Shen, Bojun Ma, Zhukuan Cheng, Zhukuan Cheng   +10 more
doaj   +1 more source

Structural analysis of the human SYCE2–TEX12 complex provides molecular insights into synaptonemal complex assembly [PDF]

Open Biology, 2012
The successful completion of meiosis is essential for all sexually reproducing organisms. The synaptonemal complex (SC) is a large proteinaceous structure that holds together homologous chromosomes during meiosis, providing the structural framework for ...
Owen R. Davies, Joseph D. Maman, Luca Pellegrini   +2 more
doaj   +1 more source

Defects in Meiotic Recombination Delay Progression Through Pachytene in Tex19.1-/- Mouse Spermatocytes [PDF]

, 2018
Recombination, synapsis, chromosome segregation and gene expression are co-ordinately regulated during meiosis to ensure successful execution of this specialised cell division.
A Chicheportiche, A Copsey, AH Peters, AM Lyndaker, B Drabent, CA Adelman, CK Cahoon, David Read, E Bolcun-Filas, E Meijering, E Testa, EA Ahmed, EF Joyce, F Baudat, F Baudat, F Carofiglio, F Yang, H Nakata, HBDP Rao, I Roig, Ian R. Adams, J Chen, J Cobb, J Reichmann, J Reichmann, J Schindelin, JA Hackett, James H. Crichton, JH Crichton, JH Crichton, JH Lammers, JM Cloutier, JMA Turner, JY An, K Daniel, L Kauppi, L Kauppi, L Wojtasz, L Wojtasz, L Xu, L-Y Lu, LH Hartwell, LK Anderson, M Barchi, M Faieta, M Fujimuro, M MacLennan, M Marcet-Ortega, N Reynolds, NM Vranis, PB Moens, PJ Romanienko, PJ Wang, PM Carlton, PS Burgoyne, R Core Team, R Öllinger, RL Meuwissen, S Kuntz, S Pacheco, S Schoenmakers, SK Mahadevaiah, SK Mahadevaiah, TJ Broering, VD Rinaldi, VV Subramanian, WM Baarends, XC Li, Y Costa, Y Tarabay, Y-H Shin, YT Kwon   +71 more
core   +1 more source

Synaptonemal Complex and Microtubule Line Profiler

, 2019
Line profiler’s purpose is to evaluate datasets in a biological/biophysical context. The software recognizes line shaped structures in image data and computes their mean position and orientation with sub-pixel accuracy. For each line a mean intensity profile is calculated.
Zwettler, Fabian U., Spindler, Marie-Christin, Reinhard, Sebastian   +2 more
openaire   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, Volume 13, Issue 4, 19 January 2026.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source

A meiotic mystery in experimental hybrids of the eastern mole vole (Ellobius tancrei, Mammalia, Rodentia)

Вавиловский журнал генетики и селекции, 2019
Chromosomal rearrangements can lead to the formation of new stable karyotypes, nevertheless changing the architectonics of the nucleus. The differences in locations might promote Robertsonian (Rb) translocations and encourage meiotic drive in favour of ...
V. G. Tambovtseva, S. N. Matveevsky, A. A. Kashintsova, A. V. Tretiakov, O. L. Kolomiets, I. Yu. Bakloushinskaya   +5 more
doaj   +1 more source