Results 71 to 80 of about 9,868 (165)

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1626-1646, June 2026.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Progress in the research of genetics and clinical manifestation of paroxysmal kinesigenic dyskinesia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Paroxysmal kinesigenic dyskinesia (PKD) is a disorder characterized by recurrent and brief attacks that are induced by sudden voluntary movement with highly clinical and genetic heterogeneity.
Xiao-jun HUANG, Li CAO, Sheng-di CHEN
doaj  

Single secretory granules of live cells recruit syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in large copy numbers. [PDF]

Proc Natl Acad Sci U S A, 2010
Before secretory vesicles undergo exocytosis, they must recruit the proteins syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in the plasma membrane. GFP-labeled versions of both proteins cluster at sites where secretory granules have docked.
Knowles MK, Barg S, Wan L, Midorikawa M, Chen X, Almers W.   +5 more
europepmc   +4 more sources

Beyond the Known and Established Neurodegenerative Effects: Roles of APOE Across a Wide Spectrum of Pathophysiological Condition

MedComm, Volume 7, Issue 6, June 2026.
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina, Samantha Maurotti, Alberto Castagna, Tiziana Montalcini, Arturo Pujia, Luca Tirinato   +5 more
wiley   +1 more source

Immunohistochemical detection of metalloproteinase-9 (MMP-9), anti-oxidant like 1 protein (AOP-1) and synaptosomal-associated protein (SNAP-25) in the cerebella of dogs naturally infected with spontaneous canine distemper

Folia Histochemica et Cytobiologica, 2011
In most viral infections of the central nervous system (CNS), the integrity of brain extracelluar matrix (ECM), oxidative stress and dysfunction in neuronal transmission may contribute to the observed pathology.
Tereza C. Cardoso, Maria C.R. Luvizotto, Henrique G. Riva, Marcília C. Pires, Flávio L.B.T. Roncatti, Sabrina D. Agostinho, Lívia C. Bregano   +6 more
doaj   +1 more source

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley   +1 more source

Activity‐based anorexia enhances glutamatergic synaptic transmission and neuronal excitability within the nucleus accumbens of female mice

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Anorexia nervosa is a severe psychiatric disorder characterized by persistent food restriction and often excessive physical activity, implicating dysfunction in neural circuits governing motivation, reward, and behavioral persistence. The nucleus accumbens (NAc) is a central component of these circuits, yet synaptic and cellular adaptations ...
Lydia G. Bailey, Connor W. Christensen, Samantha E. Weed, Mohammed Moinul Islam, Amit Thakar, Jaedyn B. Brown, Shane T. Hentges, Travis E. Brown   +7 more
wiley   +1 more source

Association of synaptosomal-associated protein 25 (SNAP-25) gene

, 2018
Background: Synaptosomal-associated protein 25 (SNAP-25) may be contribute to the pathogenesis of fibromyalgia Syndrome (FMS) by affecting the release of neurotransmitters. Objectives: We aimed to investigate the relationship between the SNAP-25 gen (DdeI = rs1051312 and MnlI = rs3746544) polymorphism and the temperament and character traits.
Dogru, A, Balkarli, A, Tepeli, E, Aydin, E, Cobankara, V   +4 more
openaire   +1 more source

Evolutionary conservation of synaptosome-associated protein 25 kDa (SNAP-25) shown by Drosophila and Torpedo cDNA clones.

Journal of Biological Chemistry, 1993
The neuron-specific proteins SNAP-25 (synaptosome-associated protein 25 kDa), synaptobrevin and syntaxin, are localized to presynaptic terminals in mammals and have been found to associate with proteins involved in vesicle docking and membrane fusion.
C, Risinger, A G, Blomqvist, I, Lundell, A, Lambertsson, D, Nässel, V A, Pieribone, L, Brodin, D, Larhammar   +7 more
openaire   +2 more sources

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Communications Chemistry
Protein conformational changes drive signal transduction to regulate cellular activities, yet monitoring of these changes in living cells remains challenging.
Huixia Jia, Lin Yang, Yu Yang, He Liu, Jia Liu, Chunfeng Shang, Zengru Di, Benzhao He, Ke Zhang   +8 more
doaj   +1 more source