Results 111 to 120 of about 29,778 (263)

EFFECT OF А PURIFIED SAPONINS' MIXTURE FROM ASTRAGALUS GLYCYPHYLLOIDES, ADMINISTERED ALONE, ON ISOLATED RAT BRAIN SYNAPTOSOMES AND HEPATOCYTES

, 2018
Purified saponins’ mixture (PSM), obtained from Astragalus glycyphylloides (family Fabaceae) was examined for possible toxic effects on isolated rat brain synaptosomes and hepatocytes when administered alone.
Magdalena Kondeva-Burdina, Vasil Manov, Ilina Krasteva, Georgi Popov, Aleksandar Shkondrov   +4 more
core   +1 more source

Astrocyte-secreted factors modulate synaptic protein synthesis as revealed by puromycin labeling of isolated synaptosomes

Frontiers in Molecular Neuroscience
The synaptic proteome can be shaped by proteins transported from the neuronal soma and/or by mRNAs that are delivered to synapses where proteins are locally synthesized. This last mechanism is known as local translation.
Aida de la Cruz-Gambra, Aida de la Cruz-Gambra, Jimena Baleriola, Jimena Baleriola   +3 more
doaj   +1 more source

Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs.

, 2001
Modafinil did not affect spontaneous and K(+)-evoked [3H]5-HT efflux from cortical synaptosomes while it increased K(+)-evoked tritium efflux from cortical slices, an action that became stronger in the presence of paroxetine. In contrast, DL-fenfluramine
FERRARO, Luca Nicola, TANGANELLI, Sergio, TOMASINI, Maria Cristina, RAMBERT F. A., ANTONELLI, Tiziana, BEBE B. W., FUXE K.   +6 more
core   +1 more source

Separation of specific fractions of synaptosomes by affinity chromatography

, 2013
The authors describe a new technique for isolation of specific fractions of synaptosomes, on the basis of their surface glycoproteins, by affinity chromatography using lectin-Sepharose columns.
García-Segura, Luis M., Martínez-Murillo, Ricardo, Martínez-Rodríguez, Ricardo   +2 more
core   +1 more source

Age-related changes in H2O2 production and bioenergetics in rat brain synaptosomes

, 2008
Detrimental changes to mitochondrial function have been shown to occur with age. In this study we examined the levels of H2O2 production, in situ mitochondrial membrane potential (Δψm), oxygen consumption (JO2) and electron transport chain (ETC) enzyme ...
Gavin P. Davey, Kilbride, Seán M., Davey, Gavin P., Jayne E. Telford, Telford, Jayne E., Seán M. Kilbride   +5 more
core   +1 more source

Effects of pressure on uptake and release of calcium by brain synaptosomes

, 1986
Uptake of radioactive calcium from guinea pig brain fractions enriched in synaptosomes could be significantly and reproducibly decreased by exposure to high pressure. Calcium efflux from preloaded synaptosomes was unaffected by pressure exposure. It was
K. K. Kumaroo, J. M. Hallenbeck, S. C. Gilman   +2 more
core   +1 more source

Thiamine, thiamine phosphates and thiamine metabolizing enzymes in synaptosomes of rat brain.

, 1990
Thiamine and thiamine mono-, pyro- and triphosphate were found at detectable levels in synaptosomes isolated from whole rat brain. Synaptosomes prepared from whole brain, cerebellum and medulla were also found to contain uridine and inosine mono- and ...
POLONI M, MAZZARELLO, PAOLO ANGELO, RINDI, GIANGUIDO, PATRINI, CESARE, LAFORENZA, UMBERTO   +4 more
core  

Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting

EMBO Journal, 2014
Christoph Biesemann, M. Grønborg, E. Luquet, Sven P. Wichert, V. Bernard, Simon R Bungers, Benjamin H. Cooper, F. Varoqueaux, Liyi Li, J. Byrne, H. Urlaub, O. Jahn, N. Brose, E. Herzog   +13 more
semanticscholar   +1 more source

Depletion of cytosolic GSH decreases the ATP levels and viability of synaptosomes from aged mice but not from young mice

, 1995
The effect of glutathione depletion on the viability of freshly isolated synaptosomes from whole brain was investigated in young and aged mice. Aging did not influence the GSH and ATP levels and the viability of these synaptosomes.
Ferrándiz, María Luisa, Díez, Araceli, Martínez, Marcos, Miquel, Jaime   +3 more
core   +1 more source

The stimulus-induced release of 5-hydroxytryptamine and tryptophan from superfused rat brain synaptosomes

, 1982
The synthesis of 5-hydroxytryptamine (5-HT) from3H-tryptophan in rat forebrain synaptosomes was studied. Synaptosomes which had been preincubated with3H-tryptophan were perfused with Krebs solution and the release of tryptophan, 5-HT and 5 ...
Suter, H. A., Wilkinson, Lawrence Stephen, Evans, T. N. W., Collard, K. J.   +3 more
core   +1 more source