Results 91 to 100 of about 29,778 (263)

Glutamate and γ-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients

, 2000
During surgical intervention in medically refractory temporal lobe epilepsy (TLE) patients, diagnosed with either mesial temporal lobe sclerosis (MTS)- or tumor (T)-associated TLE, biopsies were taken from the anterior temporal neocortex and the ...
Huffelen, A.C. van, Hoogland, G., Veelen, C.W. van, Wit, M. de, Graan, P.N.E. de, Gispen, W.H., Hens, J.J.H.   +6 more
core   +1 more source

Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes* 210

Journal of Biological Chemistry, 2002
TRPC genes encode a ubiquitous family of ion channel proteins responsible for Ca2+ influx following stimulation of G-protein-coupled membrane receptors linked to phospholipase C. These channels may be localized to large multimeric signaling complexes via
Monu Goel, W. Sinkins, W. Schilling
semanticscholar   +1 more source

Ca2+ dynamics in synaptosomes isolated from the squid optic lobe

, 2000
Synaptosomes from the optic lobes of squid (Loligo forbesi) were prepared by homogenization and allowed to settle onto glass coverslips. Synaptosomes were loaded with Ca2+ sensitive dyes (Fura-2 AM, Calcium Green-1 AM and Calcium Green-5N AM), visualized
Brown, Euan R; id_orcid, Lima, Pedro A, Benech, Juan C, Sotelo, José R   +3 more
core   +1 more source

LTP in synaptosomes does not require new protein synthesis or proteasome-dependent protein degradation.

, 2013
A, Inhibition of new protein synthesis with cycloheximide does not inhibit LTP in synaptosomes. Synaptosomes were pre-treated either with or without cycloheximide (50 µM) and stimulated as in figure 2A.
Guy Doucet (372199), Edward A. Fon (372200), Amadou T. Corera (372197)   +2 more
core   +1 more source

ATP-stimulated glutamate-dependent calcium uptake by rat synaptosomes

, 1992
The entry of Ca2+ in rat synaptosomes was followed with a Ca2+-selective electrode. Extracellular ATP is necessary for the entry which is a function of synaptosomal protein, free Ca2+ and glutamate concentrations.
Tiziana Battistin, Lauro Galzigna, Maria Bianchi, Marina Scarpa, Adelio Rigo   +4 more
core   +1 more source

Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes.

Neurochemistry International, 1990
The formation of oxygen reactive species in response to oxidative stimuli was measured in rat synaptosomes. Studies employed the non-fluorescent probe 2?,7?-dichlorofluorescin diacetate (DCFH-DA), which after de-esterification is oxidized in the presence
C. Lebel, S. Bondy
semanticscholar   +1 more source

Abnormal norepinephrine uptake and release in brain synaptosomes in chronic renal failure

, 1989
Abnormal norepinephrine uptake and release in brain synaptosomes in chronic renal failure. Abnormalities in the function of the central nervous system exist in chronic renal failure (CRF) and some of these derangements may be related to excess ...
Massry, Shaul G., Smogorzewski, Miroslaw, Campese, Vito M.   +2 more
core   +1 more source

Stimulation of Immunoreactive Insulin Release by Glucose in Rat Brain Synaptosomes [PDF]

, 1999
The effect of glucose on the release of immunoreactive insulin (IRI) in synaptosomes isolated from rat brain was studied. In the absence of glucose synaptosomes release about 4% (0.77 µIU/mg protein) of total content.
Santos, Maria, Pereira, Emilia, Carvaho, Arsélio   +2 more
core   +1 more source

810-nm Photobiomodulation Evokes Glutamate Release in Normal and Rotenone-Dysfunctional Cortical Nerve Terminals by Modulating Mitochondrial Energy Metabolism

Cells
The dysfunction of mitochondria, the primary source of cellular energy and producer of reactive oxygen species (ROS), is associated with brain aging and neurodegenerative diseases. Scientific evidence indicates that light in the visible and near-infrared
Silvia Ravera, Elisa Farsetti, Guido Maura, Manuela Marcoli, Matteo Bozzo, Chiara Cervetto, Andrea Amaroli   +6 more
doaj   +1 more source

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain

Frontiers in Cellular Neuroscience, 2017
Nerve cell connections, formed in the developing brain of mammals, undergo a well-programmed process of maturation with changes in their molecular composition over time.
Alexandra K. Suchowerska, Sandra Fok, Holly Stefen, Holly Stefen, Peter W. Gunning, Edna C. Hardeman, John Power, Thomas Fath, Thomas Fath   +8 more
doaj   +1 more source