Results 61 to 70 of about 355,526 (241)

Dual primary malignancies in Kashmir: A five-year analysis of temporal patterns, gender-specific presentations and treatment outcomes in a high gastrointestinal cancer risk population

Journal of Family Medicine and Primary Care
Patients diagnosed with cancer remain at risk of developing subsequent primary malignancies due to genetic predisposition, environmental factors, and improved survival associated with advances in diagnosis and treatment. Understanding the pattern of dual
Ubaid Jeelani, Mushood Ghulam Nabi, Asim Ahmad Dar, Gowher Ahmad Wagai, Aadil Najeed, Sheikh Owais Ahmad, Lande Sagar Janardhan, Md Mayeen Afsan Ahmad, Uzma Majeed   +8 more
doaj   +1 more source

Synchronous primary tumors amd distant metastasis detected on 18F-FDG PET in patients with head and neck carcinoma [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology
Objective(s): 18F-FDG PET/CT has been used to characterize the primary lesion and staging in head and neck cancers (HNC). However, prior studies for detecting distant metastasis and  synchronous tumors are sparse, especially in Indian context.
Nitin Gupta, Samta Kumari, Poorva Vias, Manpreet Kaur, Shalini Verma   +4 more
doaj   +1 more source

The impact of synchronous malignancies on survival in patients with early stage curable non-small-cell lung cancer

Cancer Treatment and Research Communications, 2020
BACKGROUND: To determine if synchronous extrapulmonary malignancies in early stage lung cancer impact survival and cost of care in the current era of improved therapies and diagnostics.
Amit Singnurkar, Anand Swaminath, Ur Metser, Deanna L. Langer, Gail E. Darling, Gregory R. Pond   +5 more
doaj   +1 more source

A Library for Synchronous Control Systems in Modelica [PDF]

, 2012
Based on the synchronous language elements introduced in Modelica 3.3, a library is described to utilize the new features in a convenient way for graphical model definition of sampled data systems.
Hilding Elmqvist, Otter, Martin, Martin Otter, Bernhard hiele, Thiele, Bernhard, Elmquvist, Hilding   +5 more
core   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Clinicopathological Characteristics of Multiple Primary Malignancies Involving Female Genital Tract at a Tertiary Cancer Institute of Northeast India

Journal of Mid-Life Health
Background The term “Multiple Primary Malignant Neoplasms (MPMNs)” refers to two or more unrelated primary malignant neoplasms that originate from single or different organs and occur in one patient.
Eshwarya Jessy Kaur, Debabrata Barmon, Upasana Baruah, Dimpy Begum   +3 more
doaj   +1 more source

Kaplan-Meier survival curves for synchronous and metachronous second primary malignancy (SPM) in Group A and Group B.

, 2022
Kaplan-Meier survival curves for synchronous and metachronous second primary malignancy (SPM) in Group A and Group B.
Shih-Wei Wang (172988), Ling-Feng Wang (12090961), Leong-Perng Chan (2056501), Sheng-Hsuan Lin (418082), Tzu-Yen Huang (1563109), Che-Wei Wu (6712607), Ka-Wo Lee (842346)   +6 more
core   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source