Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State
Glia, EarlyView.THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui +6 more
wiley +1 more source
Vascular Endothelial Damage: The Role of Syndecan-1 and Hyaluronan as Severity Indicators in COVID-19 [PDF]
, 2021 Azwar Anas +2 more
openalex +1 more source
Functional Cellular Anti-Tumor Mechanisms are Augmented by Genetic Proteoglycan Targeting. [PDF]
, 2020 While recent research points to the importance of glycans in cancer immunity, knowledge on functional mechanisms is lacking. In lung carcinoma among other tumors, anti-tumor immunity is suppressed; and while some recent therapies boost T-cell mediated ...
El Ghazal, Roland +5 more
core
The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance [PDF]
, 2011 The multiprotein complexes that receive and transmit axon pathfinding cues during development are essential to circuit generation. Here, we identify and characterize the Drosophila sterile α-motif (SAM) domain-containing protein Caskin, which shares ...
Broihier, Heather T +3 more
core +2 more sources
Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.ABSTRACT Background/Purpose Systemic lupus erythematosus (SLE) may impact surgical outcomes of acute cholecystitis due to immune dysfunction and systemic inflammation. This study evaluated short‐term outcomes of cholecystectomy in SLE patients using US Nationwide Readmissions Database data.
Shao Ciao Luo +6 more
wiley +1 more source
Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
, 2019 学位記番号 ...
Osawa, Sho +2 more
core
Molecular Nutrition &Food Research, EarlyView.We analyzed colostrum and breast milk from 47 mothers to see how proteins change over time and with maternal health. Colostrum had more immune proteins, while mature milk had proteins linked to growth support. Gestational diabetes and higher BMI altered the protein composition.
Timo Seitz +9 more
wiley +1 more source
Immunohistochemical analysis of syndecan-1 in leukoplakia and oral submucous fibrosis
Dental Research Journal, 2013 Background: Syndecan-1 is abundant in normal tissues and reduced in squamous cell carcinomas. Leukoplakia and oral submucous fibrosis (OSF) are oral pre-cancerous disorders that have potential for malignant transformation.
Sushant S Kamat, G S Kumar, Ajit V Koshy
doaj +1 more source
Aberrant Expression of Syndecan-1 in Cervical Cancers
Pathology and Oncology Research, 2020 Syndecan-1, is a transmembrane heparan/chondroitin sulfate proteoglycan necessary for cell-cell and cell-matrix interactions. Its decreased level on the cell surface correlates with poor prognosis in several tumor types.
Katalin Karászi +7 more
semanticscholar +1 more source
Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms
Small Science, EarlyView.This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn +4 more
wiley +1 more source