Results 121 to 130 of about 24,222,086 (313)

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig, Nasibeh Karimi, Per Larsson, Karin Ekström, Rossella Crescitelli, Anna‐Carin Olin, Cecilia Lässer   +6 more
wiley   +1 more source

Functional Cellular Anti-Tumor Mechanisms are Augmented by Genetic Proteoglycan Targeting. [PDF]

, 2020
While recent research points to the importance of glycans in cancer immunity, knowledge on functional mechanisms is lacking. In lung carcinoma among other tumors, anti-tumor immunity is suppressed; and while some recent therapies boost T-cell mediated ...
El Ghazal, Roland, Fuster, Mark M, Gupta, Purva, Johns, Scott C, Kim, So Young, Zuniga, Elina I   +5 more
core  

Reduction of syndecan‐1 expression during lip carcinogenesis

Journal of Oral Pathology & Medicine, 2009
Background:  Actinic cheilitis (AC) is an oral pre‐cancerous lesion that sometimes develops into lip squamous cell carcinoma (SCC). Syndecan‐1, a transmembrane heparan sulfate proteoglycan, modulates cell‐proliferation, adhesion, migration and angiogenesis.
Martinez, A., Spencer, M. L., Brethauer, U., Grez, P., Marchesani, F. J., Rojas, I. G.   +5 more
openaire   +4 more sources

Syndecan-1 restitution by plasma after hemorrhagic shock [PDF]

Journal of Trauma and Acute Care Surgery, 2015
Over the past seven years, there have been a number of retrospective studies demonstrating that the early and empiric use of fresh frozen plasma to patients in hemorrhagic shock and receiving a massive transfusion is beneficial.1–3 More recently a prospective observational multicenter massive transfusion study (PROMMTT), confirmed that increased ratios
Rosemary A, Kozar, Shibani, Pati
openaire   +2 more sources

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles.

JCI Insight, 2019
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF.
T. Parimon, C. Yao, D. Habiel, Lingyin Ge, S. Bora, Rena Brauer, C. Evans, T. Xie, Felix Alonso-Valenteen, L. Medina-Kauwe, D. Jiang, P. Noble, C. Hogaboam, N. Deng, O. Burgy, T. Antes, M. Königshoff, B. Stripp, S. Gharib, Peter Chen   +19 more
semanticscholar   +1 more source

Immunohistological Evaluation of Peri‐Implant Soft Tissue Grafting Using a Porcine Dermal Matrix—A Human Histological Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Introduction The aim was the immunohistological evaluation of a porcine dermal matrix (PDM) in comparison to a non‐augmented control group for peri‐implant tissue thickening. Materials and Methods This human histological study involved the placement of PDM in the test group (20 patients) during implant placement, while the control group ...
F. R. S. Michallek, M. Sluka, V. C. Landwehr, K. Vach, L. Larsson, K. Nelson, S. Nahles, F. Kernen, G. Iglhaut, T. Fretwurst   +9 more
wiley   +1 more source

Novel interactions of transglutaminase-2 with heparan sulphate proteoglycans: reflection on physiological implications [PDF]

, 2008
This mini-review brings together information from publications and recent conference proceedings that have shed light on the biological interaction between transglutaminase-2 and heparan sulphate proteoglycans. We subsequently draw hypothesis of possible
A Scarpellini, A. Scarpellini, AC Parsons, AD Cardin, B Mearns, C Zehe, DC Sane, DC Sane, E Verderio, E Verderio, E. A. M. Verderio, EA Verderio, ES Oh, F Echtermeyer, F Echtermeyer, G Fan, H Morita, J Filmus, J Hang, JF Qiu, JR Bishop, K Ishiguro, K Small, L Fesus, L Lorand, L Lorand, L Pellegrini, M Griffin, M Griffin, M Signorini, MA Stepp, MR Morgan, NJ Skill, P Grenard, P Stephens, PH Seeberger, Q Fan, R Gallo, RJ Richards, S Gambetti, S Yung, SA Wilcox-Adelman, SS Akimov, T. S. Johnson, TS Johnson, TS Johnson, TS Johnson, TS Johnson, V Gentile, X Li, XD Ren, ZA Haroon   +51 more
core   +1 more source

CD138 (Syndecan-1) Expression in Bone-Forming Tumors [PDF]

American Journal of Clinical Pathology, 2012
CD138 (syndecan-1), a cell surface proteoglycan, is sensitive and specific for plasmacytic differentiation in hematologic disorders. Expression of CD138 has been observed in a majority of epithelial neoplasms and, rarely, soft tissue tumors. However, its expression in bone tumors has not been evaluated.
Amberly L, Nunez, Gene P, Siegal, Vishnu V B, Reddy, Shi, Wei   +3 more
openaire   +2 more sources

Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma

Clinical Cancer Research, 2019
Purpose: Liquid biopsy has great potential to improve the management of brain tumor patients at high risk of surgery-associated complications. Here, the aim was to explore plasma extracellular vesicle (plEV) immunoprofiling as a tool for noninvasive ...
Vineesh Indira Chandran, C. Welinder, A. Månsson, S. Offer, E. Freyhult, M. Pernemalm, S. Lund, S. Pedersen, J. Lehtiö, G. Marko‐Varga, M. Johansson, E. Englund, P. Sundgren, M. Belting   +13 more
semanticscholar   +1 more source

Elevated Plasma Concentrations of Syndecan-1 Do Not Correlate With Increased Capillary Leakage of 20% Albumin.

Anesthesia and Analgesia, 2020
BACKGROUND Preclinical experiments show that an inflammatory reaction causes degradation of the endothelial glycocalyx layer and accelerated capillary leakage of albumin and fluid.
R. Hahn, Markus Zdolsek, Camilla Krizhanovskii, Stelia Ntika, J. Zdolsek   +4 more
semanticscholar   +1 more source