Results 11 to 20 of about 23,952,755 (264)
The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors [PDF]
Frontiers in Oncology, 2013 Proteoglycans and in particular the syndecans are involved in the differentiation process across the epithelial-mesenchymal axis, principally through their ability to bind growth factors and modulate their downstream signalling.
Tünde eSzatmári, Katalin eDobra
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High Preoperative Serum Syndecan-1, a Marker of Endothelial Glycocalyx Degradation, and Severe Acute Kidney Injury after Valvular Heart Surgery [PDF]
Journal of Clinical Medicine, 2020 Degradation of endothelial glycocalyx (EG) is associated with inflammation and endothelial dysfunction, which may contribute to the development of acute kidney injury (AKI). We investigated the association between a marker of EG degradation and AKI after
Hye-Bin Kim +5 more
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Frontiers in Pharmacology, 2022 Purpose: We aimed to examine the prognostic value of syndecan-1 as a marker of glycocalyx injury in patients with acute ischemic stroke (AIS) receiving rt-PA intravenous thrombolysis.Methods: The study included 108 patients with AIS treated with rt-PA ...
Fangfang Zhao +20 more
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Frontiers in Medicine, 2021 Glycocalyx is present on the surface of healthy endothelium, and the concentration of serum syndecan-1 can serve as an injury marker. This study aimed to assess endothelial injury using serum syndecan-1 as a marker of endothelial glycocalyx injury in ...
Keigo Kusuzawa +36 more
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Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis.
PLoS ONE, 2021 The endothelial glycocalyx (EG) is essential for proper function of the endothelium and for vascular integrity, but its role in premature atherogenesis in rheumatoid arthritis (RA) has not been studied yet.
Gia Deyab +10 more
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Serum Syndecan-1 is Associated With Kidney and Cardiovascular Outcomes in Idiopathic Nephrotic Syndrome [PDF]
Kidney International ReportsIntroduction: Idiopathic nephrotic syndrome (INS) is associated with important kidney and cardiovascular morbidities. We tested the hypothesis that serum syndecan-1, a marker of endothelial glycocalyx injury, can help identify patients at risk for ...
Colin Bauer +10 more
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PLoS ONE, 2021 Syndecan-1 is found in the endothelial glycocalyx and is released into the bloodstream during stressed conditions, including severe diseases such as acute kidney injury, chronic kidney disease, and cardiovascular disease.
Yuichiro Kitagawa +29 more
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A novel role for syndecan-3 in angiogenesis [v1; ref status: indexed, http://f1000r.es/2g6] [PDF]
F1000Research, 2013 Syndecan-3 is one of the four members of the syndecan family of heparan sulphate proteoglycans and has been shown to interact with numerous growth factors via its heparan sulphate chains.
Giulia De Rossi, James R. Whiteford
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Frontiers in Cell and Developmental Biology, 2021 Basal-like breast cancer is characterized by an aggressive clinical outcome and presence of metastasis, for which effective therapies are unavailable.
Satomi Nadanaka +2 more
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Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas [PDF]
Analytical Cellular Pathology, 2018 Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. E-Cadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas ...
Ramón G. Carreón-Burciaga +5 more
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