Results 41 to 50 of about 23,952,755 (264)
Blood, 2021 Plasma cells no longer express a B-cell-antigen-receptor and are hence deprived of signals crucial for survival throughout B-cell development. Instead, normal plasma cells, as well as their malignant myeloma counterparts, heavily rely on communication ...
Z. Ren, M. Spaargaren, S. Pals
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Novel genes and pathways modulated by syndecan-1: implications for the proliferation and cell-cycle regulation of malignant mesothelioma cells. [PDF]
PLoS ONE, 2012 Malignant pleural mesothelioma is a highly malignant tumor, originating from mesothelial cells of the serous cavities. In mesothelioma the expression of syndecan-1 correlates to epithelioid morphology and inhibition of growth and migration.
Tünde Szatmári +7 more
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Plasma concentrations of syndecan‐1 are dependent on kidney function
Acta Anaesthesiologica Scandinavica, 2021 Elevated plasma concentrations of syndecan‐1 and heparan sulfate in studies of trauma, sepsis, and major surgery are commonly assumed to indicate acute glycocalyx degradation. We explored a possible role of the kidneys for these elevations.
R. Hahn, Markus Zdolsek, J. Zdolsek
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BMC Cancer, 2008 Background Syndecan-1 is a transmembrane proteoglycan with important roles in cell-cell and cell-extracellular matrix adhesion and as a growth factor co-receptor.
Skacel Marek +2 more
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Journal of Histochemistry and Cytochemistry, 2020 Both heparanase and syndecan-1 are known to be present and active in disease pathobiology. An important feature of syndecan-1 related to its role in pathologies is that it can be shed from the surface of cells as an intact ectodomain composed of the ...
S. Rangarajan +6 more
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Nuclear Syndecan-1 Regulates Epithelial-Mesenchymal Plasticity in Tumor Cells
Biology, 2021 Simple Summary The major cause of death in cancer is that tumor cells metastasize (i.e., spread to vital organs such as the lungs and liver). Our knowledge of how metastasis occurs is incomplete and consequently, there is a lack of therapeutic strategies
Ashish Kumar-Singh +8 more
semanticscholar +1 more source
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. [PDF]
PLoS ONE, 2014 BACKGROUND: The heparan sulfate proteoglycan syndecan-1 (CD138) was shown to regulate inflammatory responses by binding chemokines and cytokines and interacting with adhesion molecules, thereby modulating leukocyte trafficking to tissues.
Paulina M Kowalewska +2 more
doaj +1 more source
S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation. [PDF]
, 2015 Cigarette smoke induces injury and neutrophilic inflammation in the airways of smokers. The stability and activity of inflammatory effectors, IL8 and neutrophil elastase (NE), can be prolonged by binding to airway heparan sulfate (HS)/syndecan-1, posing ...
Chan, CH +5 more
core +1 more source
Scientific Reports, 2021 This study aimed to compare the effects of volatile anesthesia and total intravenous anesthesia (TIVA) on syndecan-1 shedding in patients with gastric cancer undergoing minimally invasive gastrectomy.
Na Young Kim +6 more
semanticscholar +1 more source
The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]
, 2015 We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa +10 more
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