Results 71 to 80 of about 24,222,086 (313)

Biomarker profiles of acute heart failure patients with a mid-range ejection fraction [PDF]

open access: yes, 2017
OBJECTIVES: In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a ...
Bloomfield, Daniel M   +16 more
core   +2 more sources

Plasma concentrations of syndecan‐1 are dependent on kidney function

open access: yesActa Anaesthesiologica Scandinavica, 2021
Elevated plasma concentrations of syndecan‐1 and heparan sulfate in studies of trauma, sepsis, and major surgery are commonly assumed to indicate acute glycocalyx degradation. We explored a possible role of the kidneys for these elevations.
R. Hahn, Markus Zdolsek, J. Zdolsek
semanticscholar   +1 more source

Induction of adhesion-dependent signals using low-intensity ultrasound. [PDF]

open access: yes, 2012
In multicellular organisms, cell behavior is dictated by interactions with the extracellular matrix. Consequences of matrix-engagement range from regulation of cell migration and proliferation, to secretion and even differentiation.
Bass, M. D., Harrison, A., Roper, J.
core   +1 more source

Distribution of syndecan-1 protein in developing mouse teeth

open access: yesFrontiers in Physiology, 2015
Syndecan-1 is a cell surface proteoglycan involved in the regulation of various biological processes such as proliferation, migration, condensation and differentiation of cells, intercellular communication and morphogenesis.
Anna eFilatova   +2 more
doaj   +1 more source

Endothelial glycocalyx during early reperfusion in patients undergoing cardiac surgery.

open access: yesPLoS ONE, 2021
BackgroundExperimental cardiac ischemia-reperfusion injury causes degradation of the glycocalyx and coronary washout of its components syndecan-1 and heparan sulfate.
Arie Passov   +5 more
doaj   +1 more source

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]

open access: yes, 2013
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Burhan, I   +6 more
core   +1 more source

Detection of Syndecan-1 and Heparanase-1 Genes in Esophageal Carcinoma by Quantitative RT-PCR

open access: yesCancer Biology & Medicine, 2010
OBJECTIVE To quantitatively explore the expression of Syndecan-1 and heparanase-1 in esophageal cancer tissue as well as their relationship with the clinicopathological factors, in order to evaluate their roles in tumor invasion and metastasis.METHODS
Jun-li SI, Yu-qin QI, Jing-yuan CUI
doaj   +1 more source

Targeting syndecan-1 in breast cancer inhibits osteoclast functions through up-regulation of osteoprotegerin

open access: yesJournal of Bone Oncology, 2014
Background: Breast cancer often metastasizes into bone and leads to osteolytic lesions. The underlying mechanisms, however, are complex and not fully understood.
Peggy Benad-Mehner   +5 more
doaj   +1 more source

Functional Characterization of Mouse Syndecan-1 Promoter [PDF]

open access: yesJournal of Biological Chemistry, 1996
The members of the syndecan family are temporally and spatially expressed heparan sulfate proteoglycans of various tissues, where they mediate extracellular influences on cell morphology and behavior. Functional characterization of the mouse syndecan-1 promoter was carried out in order to elucidate the mechanisms involved in the maintenance of the high
T, Vihinen   +4 more
openaire   +2 more sources

Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration. [PDF]

open access: yesPLoS ONE, 2011
BackgroundSyndecans are proteoglycans whose core proteins have a short cytoplasmic domain, a transmembrane domain and a large N-terminal extracellular domain possessing glycosaminoglycan chains. Syndecans are involved in many important cellular processes.
Fang Zong   +9 more
doaj   +1 more source

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