Results 81 to 90 of about 24,222,086 (313)

Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration. [PDF]

, 2016
Our previous reports indicate that ligand-induced αVβ3 integrin and Syndecan-4 engagement increases focal adhesion formation and migration of astrocytes.
Alvarez, A., Burgos-Bravo, F., Cárdenas, A., Kong, M., Lagos-Cabré, R., Leyton, L., Quest, A.F., Schneider, P.   +7 more
core   +2 more sources

Syndecan-1 and syndecan-2 play key roles in herpes simplex virus type-1 infection

Journal of General Virology, 2010
Herpes simplex virus type 1 (HSV-1) is an important human pathogen and a leading cause of infectious blindness in the developed world. HSV-1 exploits heparan sulfate proteoglycans (HSPG) for attachment to cells. While the significance of heparan sulphate (HS) moieties in HSV-1 infection is well established, the role of specific proteoglycan core ...
Sarolta, Bacsa, Ghadah, Karasneh, Sandor, Dosa, Jian, Liu, Tibor, Valyi-Nagy, Deepak, Shukla   +5 more
openaire   +2 more sources

Syndecan-1 [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Objective— Arterial injury induces smooth muscle cell (SMC) proliferation, migration, and intimal accumulation of cells and extracellular matrix. These processes are regulated by the administration of the glycosaminoglycans heparin and heparan sulfate, but little is known about the role of endogenous
Nozomi, Fukai, Richard D, Kenagy, Lihua, Chen, Lu, Gao, Guenter, Daum, Alexander W, Clowes   +5 more
openaire   +2 more sources

Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression

Journal of Histochemistry and Cytochemistry, 2020
Both heparanase and syndecan-1 are known to be present and active in disease pathobiology. An important feature of syndecan-1 related to its role in pathologies is that it can be shed from the surface of cells as an intact ectodomain composed of the ...
S. Rangarajan, J. R. Richter, R. P. Richter, Shyam Bandari, K. Tripathi, I. Vlodavsky, R. Sanderson   +6 more
semanticscholar   +1 more source

A syndecan és decorin proteoglikánok kóroki szerepének modellezése májbetegségekben = Experimental models to study the significance of syndecan-1 and decorin in the development of liver diseases [PDF]

, 2007
Az elmúlt 4 évben olyan modellrendszereket dolgoztunk ki, melyekben a proteoglikánok kifejeződését megváltoztattuk. Kialakitottunk egy decorin -/- TGF béta-1 +/- kettős transzgén egértörzset, melyen a cirrhosis és a hepatokarcinogenezis eseményeit ...
Kovalszky, Ilona, Nagy, Péter, Szilák, László   +2 more
core  

Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character [PDF]

, 2018
Background Heparan sulfate proteoglycans (HSPGs) are complex molecules which play a role in the invasion and growth and metastatic properties of cancerous cells.
Castañón de la Torre, Sonia, Crespo Susperregui, Ainara, Fernández Vega, Iván, García Fernández, Beatriz, García Suárez, Olivia, Quirós Fernández, Luis Manuel, Solis Hernández, María Pilar   +6 more
core   +2 more sources

Syndecan-1 Promotes Hepatocyte-Like Differentiation of Hepatoma Cells Targeting Ets-1 and AP-1

Biomolecules, 2020
Syndecan-1 is a transmembrane heparan sulfate proteoglycan which is indispensable in the structural and functional integrity of epithelia. Normal hepatocytes display strong cell surface expression of syndecan-1; however, upon malignant transformation ...
Péter Hollósi, Lóránd Váncza, Katalin Karászi, Katalin Dobos, Bálint Péterfia, Enikő Tátrai, Péter Tátrai, Tibor Szarvas, Sándor Paku, László Szilák, Ilona Kovalszky   +10 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Physiological and anatomical aspects of the reproduction of mice with reduced Syndecan-1 expression

Reproductive Biology and Endocrinology, 2019
Background Syndecan-1 is a heparan sulfate proteoglycan acting as a co-receptor for cytokines and growth factors mediating developmental, immunological and angiogenic processes.
Christina Gougoula, Alexandra P. Bielfeld, Sarah J. Pour, Jan-S. Krüssel, Martin Götte, W. Peter M. Benten, Dunja M. Baston-Büst   +6 more
doaj   +1 more source

Application of Force to a Syndecan-4 Containing Complex With Thy-1–αVβ3 Integrin Accelerates Neurite Retraction

Frontiers in Molecular Biosciences, 2020
Inflammation contributes to the genesis and progression of chronic diseases, such as cancer and neurodegeneration. Upregulation of integrins in astrocytes during inflammation induces neurite retraction by binding to the neuronal protein Thy-1, also known
Francesca Burgos-Bravo, Francesca Burgos-Bravo, Francesca Burgos-Bravo, Samuel Martínez-Meza, Samuel Martínez-Meza, Andrew F. G. Quest, Andrew F. G. Quest, Christian A. M. Wilson, Lisette Leyton, Lisette Leyton   +9 more
doaj   +1 more source