Results 61 to 70 of about 3,936,779 (293)
Goldenhar syndrome: A case report and review
CHRISMED Journal of Health and Research, 2017 Goldenhar syndrome (GS) is also known as hemifacial microsomia or oculo-auriculo-vertebral dysplasia. This condition mainly affects the oral cavity, eyes, ear, and vertebrae. This is a rare congenital anomaly.
Sonika Achalli +4 more
doaj +1 more source
Anticardiolipin syndrome: antiphospholipid syndrome [PDF]
Clinical Medicine, 2001 La detection d'anticorps antiphospholipides est a l'origine du syndrome des antiphospholipides caracterise par des pathologies vasculaires et des fausse-couches chez la femme ...
openaire +3 more sources
Overlap syndrome: A real syndrome? [PDF]
Clinical Liver Disease, 2014 Autoimmune liver diseases are rare and chronic and exert a significant burden on quality and quantity of life. The failure to understand the true etiopathogenesis of disease leaves clinicians diagnosing patients based on collective positive and negative clinical findings, such that three particular autoimmune diseases are apparent (Table 1).
Gideon M. Hirschfield, Debashis Haldar
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Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Nahoum Index in Brachyfacial Patients: A Pilot Study
Turkish Journal of Orthodontics, 2020 Objective:Our aim is to test the Nahoum Index as a support in the cephalometric study of vertical dimension and therapeutic orientation in adult patients suffering from Class II malocclusion, deep bite, or short face syndrome.Methods:Twenty-three ...
Chiara Vompi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová +14 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2010 The Schnitzler syndrome is a rare and underdiagnosed entity which is considered today as being a paradigm of an acquired/late onset auto-inflammatory disease. It associates a chronic urticarial skin rash, corresponding from the clinico-pathological viewpoint to a neutrophilic urticarial dermatosis, a monoclonal IgM component and at least 2 of the ...
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