Results 1 to 10 of about 2,222 (191)

Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives [PDF]

Biomolecules
Glucocorticoids (GCs) are routinely used to treat hematological malignancies; however, long-term treatment with GCs can lead to atrophic and metabolic adverse effects.
Ekaterina M. Zhidkova, Evgeniya S. Oleynik, Ekaterina A. Mikhina, Daria V. Stepanycheva, Diana D. Grigoreva, Lyubov E. Grebenkina, Kirill V. Gordeev, Ekaterina D. Savina, Andrey V. Matveev, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya   +10 more
doaj   +5 more sources

Synephrine potentiates lidocaine‐induced cutaneous analgesia via α‐adrenergic receptors in male rats [PDF]

Physiological Reports
This study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine.
An‐Kuo Chou, Chong‐Chi Chiu, Kuo‐Sheng Liu, Yu‐Wen Chen, Ching‐Hsia Hung, Jhi‐Joung Wang   +5 more
doaj   +3 more sources

p-Synephrine: an overview of physicochemical properties, toxicity, biological and pharmacological activity [PDF]

EXCLI Journal : Experimental and Clinical Sciences
p-Synephrine is a popular ingredient in dietary supplements. It is also found in trace amounts in living organisms. It is advertised as a weight loss supplement and it is supposed to improve performance in sports.
Maciej Kulawik, Kaja Bajewska, Anna Kulawik   +2 more
doaj   +4 more sources

Citrus aurantium L. and synephrine improve brown adipose tissue function in adolescent mice programmed by early postnatal overfeeding [PDF]

Frontiers in Nutrition, 2023
Introduction and aimsObesity is a multifactorial condition with high health risk, associated with important chronic disorders such as diabetes, dyslipidemia, and cardiovascular dysfunction. Citrus aurantium L. (C. aurantium) is a medicinal plant, and its
Andressa Cardoso Guimarães, Egberto Gaspar de Moura, Stephanie Giannini Silva, Bruna Pereira Lopes, Iala Milene Bertasso, Carla Bruna Pietrobon, Fernanda Torres Quitete, Tayanne de Oliveira Malafaia, Érica Patrícia Garcia Souza, Patrícia Cristina Lisboa, Elaine de Oliveira   +10 more
doaj   +2 more sources

Bio inspired assessment of titanium-organic framework and exosome-constructed p-Synephrine carriage: pursuing the PI3K/mTOR pathway in a simulated periodontitis [PDF]

Scientific Reports
Periodontitis, a chronic inflammatory disease, is driven by bacterial infection and oxidative stress, leading to tissue destruction and potential tooth loss.
Mohamed S. Kishta, Abdelrahman H. Elshaar, Rawan N. Makled, Ghada A. Abdel-Aleem, Mirhan N. Makled, Reda M. Abdelhameed   +5 more
doaj   +2 more sources

Supercritical CO₂ Antisolvent Fractionation of Citrus aurantium Flower Extracts: Enrichment and Characterization of Bioactive Compounds [PDF]

Plants
This study investigates the valorisation of sour orange (Citrus aurantium L.) flowers using supercritical antisolvent fractionation (SAF) with CO2 as an antisolvent.
Dhekra Trabelsi, José F. Martínez-López, Manef Abderrabba, José S. Urieta, Ana M. Mainar   +4 more
doaj   +2 more sources

Transcriptome analysis of Citrus Aurantium L. to study synephrine biosynthesis during developmental stages [PDF]

PeerJ
Citrus aurantium L., sometimes known as “sour orange,” is an important Chinese herb with young, immature fruits, or “zhishi,” that are high in synephrine.
Can Zhong, Xitao Yang, Juan Niu, Xin Zhou, Jiahao Zhou, Gen Pan, Zhimin Sun, Jianhua Chen, Ke Cao, Mingbao Luan   +9 more
doaj   +3 more sources

Preparation, quality evaluation and preliminary pharmacokinetic-pharmacodynamic studies of synephrine dry powder inhaler [PDF]

Drug Delivery
Acute lung injury (ALI) is a lung disease characterized by pulmonary edema caused by an excessive inflammatory response within the lungs and disruption of the alveolar capillary barrier, with a high morbidity and mortality rate in critically ill patients.
Jiming Ke, Shenao Li, Miaomiao Zi, Jing Zhang, Shan Huang, Wenhui Luo, Hailun Han, Jiwen Zhang, Can Peng   +8 more
doaj   +2 more sources

Effects of Different Citrus Varieties and Harvesting Time on the Quality of Citrus Dark Tea [PDF]

Foods
The genus Citrus consists of Tangerines (Citrus × reticulata), Mandarins (Citrus × reticulata), Oranges (Citrus × sinensis), Grapefruits (Citrus maxima), Lemons (Citrus × limon), and other citrus fruits.
Fuwei Guo, Yuanfang Jiao, De Zhang, Zhi Yu, Dejiang Ni, Han Huang, Yuqiong Chen   +6 more
doaj   +2 more sources

Comparison of physicochemical, phytochemical, and volatile profiles, and bioactivities of citrus wines brewed from different varieties [PDF]

Food Chemistry: X
This study comprehensively investigated the physicochemical and functional properties, and flavor profiles of citrus wines brewed from five distinct cultivars: Citrus reticulata cv. ‘Dahongpao’ (CRDW), C. reticulata ‘Chun Jian’ (CRCW), C.
Xun Fu, Qingqing Fu, Zhirong Wang, Qingyu Nie, Xiaoqing Yin, Wenling Zhang   +5 more
doaj   +2 more sources