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Structure of synephrine monohydrogenphosphate monohydrate

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1982
C9H14NO~-.HPOE-.H2 O, M r -- 450.4, monoclinic, P21/n, a = 12.108(4), b = 8.402(2), c = 21.549 (6)A, fl = 99.67 (3) °, Z = 4, D e = 1.384 Mg m -3, Cu Ka radiation, 2 = 1.54184 A,/z(Cu Ka) = 1.588 mm -I, V-- 2161.1A 3, F(000) = 960. The structure was solved by direct methods and refined by full-matrix least-squares calculations to a final R = 0.056 for ...
J. K. Dattagupta   +2 more
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PHENYLEPHRINE (NEO-SYNEPHRINE®) OINTMENT

A.M.A. Archives of Ophthalmology, 1952
PHENYLEPHRINE (neo-synephrine®) hydrochloride was first described as a therapeutic agent in ophthalmology by Heath in 1936. 1 The more recent literature has suggested additional uses for this drug. 2 More widespread and frequent use of phenylephrine has been somewhat limited by the unsatisfactory preparations now on the market.
R H, BEDROSSIAN, J W, DEICHLER
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Concentrations of p-synephrine in fruits and leaves of Citrus species (Rutaceae) and the acute toxicity testing of Citrus aurantium extract and p-synephrine

Food and Chemical Toxicology, 2008
Dietary supplements containing bitter orange unripe fruit extract/p-synephrine are consumed worldwide for lose weight. This study were conducted to determine the concentration of p-synephrine in unripe fruits and leaves from Citrus aurantium Lin, C. sinensis Osbeck, C. deliciosa Ten, C. limon Burm and C.
A T Henriques, Solange Cristina Garcia
exaly   +3 more sources

Characterization of antidepressant-like effects of p -synephrine stereoisomers

Naunyn-Schmiedeberg's Archives of Pharmacology, 2001
We previously reported that p-synephrine has antidepressant-like activity in the murine models of forced swimming and tail suspension. In the present study, we characterized antidepressant-like effects of p-synephrine stereoisomers in both in vivo and in vitro systems. In the tail suspension test, S-(+)-p-synephrine (3 mg/kg, p.o.) reduced the duration
Kee-Won Kim   +2 more
exaly   +3 more sources

Sensitive determination of synephrine by flow‐injection chemiluminescence

Luminescence, 2005
AbstractIt was found that light emission produced by the oxidation of luminol by potassium ferricyanide in basic medium was enhanced by synephrine, an anti‐obesity drug. The optimum conditions for this chemiluminescent reaction were studied in detail in a flow injection system and employed in a new, simple and rapid method for the determination of ...
Qian, Li, Chengzhi, Huang, Yuming, Huang
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Necrosis Following Intravenous Use of Neo-Synephrine

New England Journal of Medicine, 1954
INTRAVENOUS administration of arterenol (levophed or nor-epinephrine) has been reported to cause tissue necrosis.
E C, PEIRCE, V B, POLLEY
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Conformational Analysis of Octopamine and Synephrine in the Gas Phase

The Journal of Physical Chemistry A, 2013
Four and six conformers of the neurotransmitters octopamine and synephrine, respectively, have been identified in the gas phase using a laser ablation device in combination with a molecular-beam Fourier transform microwave spectrometer operating in the 4-10 GHz frequency range.
Carlos, Cabezas   +7 more
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m‐Synephrine: Normal Occurrence in Adrenal Gland

Journal of Neurochemistry, 1980
Abstract: Gas chromatography‐mass spectrometry‐selected ion monitoring has been used to identify m‐synephrine (phenylephrine) in bovine adrenal gland. After ion exchange chromatography, m‐synephrine was converted to its N‐trifluoroacetyl‐O‐trifluoroacetoxy derivative and identified by retention time and relative intensities of the two characteristic ...
J M, Midgley   +3 more
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Gesundheitliche Risiken von Synephrin in Nahrungsergänzungsmitteln

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2017
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. It is often added to dietary supplements intended for weight loss and enhancement of sports performance, typically in the form of Citrus aurantium extracts and in many cases in combination with caffeine.
Nadiya Bakhyia   +6 more
openaire   +1 more source

Establishing an Artificial Pathway for the Biosynthesis of Octopamine and Synephrine

ACS Synthetic Biology
In this study, we designed an artificial pathway composed of tyramine β-hydroxylase (TBH) and phenylethanolamine N-methyltransferase (PNMT) for the biosynthesis of both octopamine and synephrine. As most TBH and PNMT originate from eukaryotic animals and plants, the heterologous expression and identification of functional TBH and PNMT are critical for ...
Jiao Feng   +5 more
openaire   +2 more sources

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