Results 101 to 110 of about 99,242 (296)

Interfacial synergism of Pd-decorated BiOCl ultrathin nanosheets for the selective oxidation of aromatic alcohols

, 2018
Pd-decorated BiOCl ultrathin nanosheets exhibited improved photocatalysis for the selective oxidation of aromatic alcohols due to the remarkable interfacial synergism.
Peng Gao, Renshan Wang, Liangzhi Shao, Xiaoping Dong, Fugang Zhao, Benxia Li, Zhengquan Li   +6 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

SYNERGISM AND DRUG-RECEPTOR

Japanese Journal of Pharmacology, 1964
In the study of the drug-receptor interaction, the analysis of the mode of drugantagonism had been the objects of the principal interests, and the drug-synergism had only been remarked in passing (1). Veldstra (2) mentioned the relation between drug receptor and synergism in his extensive review on “Synergism and Potentiation”.
TAKAGI, KEIJIRO, TAKAYANAGI, ISSEI
openaire   +3 more sources

Synergism pattern switch triggered by psychological stress.

, 2013
In the no or low psychological stress environment (i.e. VIP or epinephrine set close to 0 in the simulation), the index was less than 1, which indicated that BADS112A plus LY294002 has synergistic effect in the whole dose region we considered. Whereas as
George Kulik (371780), Jiguang Bao (493309), Xiaobo Zhou (10386), Kyle C. Nelson (454371), Xiaoqiang Sun (493308), King Chuen Li (493310)   +5 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Multifunctional Antioxidants with High Activity at Elevated Temperatures Based on Intramolecular Synergism

, 2018
Multifunctional antioxidants with three active fragments were prepared through a simple two-step synthesis process. These novel compounds exhibited higher efficiency when inhibiting the oxidation of hydrocarbons compared to commercial products at 180 ...
Yu, Shasha, Liu, Shenggao
core  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Investigating synergism in critical micelle concentration of anionic-nonionic surfactant mixtures: Surface versus interfacial tension techniques [PDF]

, 2009
In this research, anionic (SDS) and nonionic (TX100) surfactant mixtures (1:2, 1:1, 2:1; TX100: SDS mass ratios) were evaluated for possible synergism in Critical Micelle Concentation (CMC).
Muherei, Mazen Ahmed, Junin, Radzuan
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source