Results 31 to 40 of about 169,807 (345)

Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells. [PDF]

, 2010
The HOX genes encode a family of transcription factors that are dysregulated in several malignancies and have been implicated in oncogenesis and cancer cell survival.
Daniels, TR, Morgan, R, Neacato, II, Pandha, HS, Penichet, ML, Rodríguez, JA   +5 more
core   +1 more source

In-vitro evaluation of different antimicrobial combinations with and without colistin against carbapenem-resistant acinetobacter baumannii [PDF]

, 2019
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different antimicrobial combinations (with and without colistin, COL) against ...
De Angelis, Massimiliano, Garzoli, Stefania, Marzuillo, Carolina, Mastroianni, Claudio M., Oliva, Alessandra, Ragno, Rino, Vullo, Vincenzo   +6 more
core   +1 more source

Top coal caving mining technique in thick coal seam beneath the earth dam

International Journal of Mining Science and Technology, 2017
It is important to study the mining technology under structures for raising the coal resources recovery ratio. Based on the geological and mining conditions, the top coal caving harmonic mining technique in thick coal seam beneath the earth dam was put ...
Wenbing Guo, Yi Tan, Erhu Bai
doaj   +1 more source

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

Molecular Cancer, 2017
Background Enhancing the antitumor activity of the DNA-damaging drugs is an attractive strategy to improve current treatment options. Trabectedin is an isoquinoline alkylating agent with a peculiar mechanism of action.
Ymera Pignochino, Federica Capozzi, Lorenzo D’Ambrosio, Carmine Dell’Aglio, Marco Basiricò, Marta Canta, Annalisa Lorenzato, Francesca Vignolo Lutati, Sandra Aliberti, Erica Palesandro, Paola Boccone, Danilo Galizia, Sara Miano, Giulia Chiabotto, Lucia Napione, Loretta Gammaitoni, Dario Sangiolo, Maria Serena Benassi, Barbara Pasini, Giovanna Chiorino, Massimo Aglietta, Giovanni Grignani   +21 more
doaj   +1 more source

Effect of Sequential Inoculation of Tetragenococcus halophilus and Wickerhamomyces anomalus on the Flavour Formation of Early-Stage Moromi Fermented at a Lower Temperature

Foods, 2023
Microbial inoculation in moromi fermentation has a great influence on the physicochemical and flavour properties of soy sauces. This work investigated the effect of inoculating Tetragenococcus halophilus and Wickerhamomyces anomalus on the flavour ...
Xinzhi Li, Xinyu Xu, Changzheng Wu, Xing Tong, Shiyi Ou   +4 more
doaj   +1 more source

Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death

Marine Drugs, 2021
Myeloid leukemia is a hematologic neoplasia characterized by a clonal proliferation of hematopoietic stem cell progenitors. Patient prognosis varies depending on the subtype of leukemia as well as eligibility for intensive treatment regimens and ...
Pavel Spirin, Elena Shyrokova, Timofey Lebedev, Elmira Vagapova, Polina Smirnova, Alexey Kantemirov, Sergey A. Dyshlovoy, Gunhild von Amsberg, Maxim Zhidkov, Vladimir Prassolov   +9 more
doaj   +1 more source

In Vitro Synergism Effect of an Aqueous Garlic Extracts against Six Commonly Clinical Isolated Candida Species [PDF]

Iranian Journal of Public Health, 2007
Background: The growth of different microorganisms including bacteria, fungi and viruses has been inhibited by garlic extracts in many studies. The antifungal activity of aqueous garlic extract was investigated in an in vitro system using broth ...
A A Jafari, A Fatahi Bafghi, MH Anvari, H Zarrinfar   +3 more
doaj   +1 more source

Silver Nanoparticles Enhance Antimicrobial Efficacy of Antibiotics and Restore That Efficacy against the Melioidosis Pathogen

Antibiotics, 2021
Melioidosis is an infectious disease caused by Gram-negative bacillus bacteria Burkholderia pseudomallei. Due to the emerging resistance of B. pseudomallei to antibiotics including ceftazidime (CAZ), the development of novel antibiotics and alternative ...
Sathit Malawong, Saengrawee Thammawithan, Pawinee Sirithongsuk, Sakda Daduang, Sompong Klaynongsruang, Pamela T. Wong, Rina Patramanon   +6 more
doaj   +1 more source

A dual origin for Bcr-Abl gene translocation/fusion as dynamics of synergism of the hematopoietic stem cell and hemangioblast in chronic myeloid leukemia [PDF]

, 2015
Contextual BCR-ABL tyrosine kinase over-activity determines in formulated fashion the emergence of proliferation and anti-apoptosis that arise largely as derived phenomena of otherwise homeostatic mechanisms of the c-ABL gene within hematopoietic ...
Agius, Lawrence M.
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source