Results 61 to 70 of about 99,242 (296)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2021 While the concept of interfacial tension synergism in surfactant mixtures is well established, little attention has been paid to the possibility of synergistic effects on the interfacial rheology of mixed surfactant systems.
Stephen Law (6155762) +3 more
core +2 more sources
Molecules, 2023 The aim of the study was to investigate the antibacterial effects of essential oils isolated from different cultivars and morphological parts of lavender (Lavandula angustifolia Mill.) in combination with the aminoglycoside antibiotic gentamicin. This in
Michalina Adaszyńska-Skwirzyńska +5 more
doaj +1 more source
Synergizing in Cyberinfrastructure Development [PDF]
Computer Supported Cooperative Work (CSCW), 2010 This paper investigates the work of creating infrastructure, using as a case study the development of cyberinfrastructure for metagenomics research. Specifically, the analysis focuses on the role of embeddedness in infrastructure development. We expand on the notion of human infrastructure to develop the concepts of synergizing, leveraging, and ...
Matthew J. Bietz +2 more
openaire +3 more sources
Synergism in anticorrosive paints [PDF]
, 2016 The present work depicts synergism anticorrosive behaviour between zinc hypophosphite and zinc phosphate in a commercial pigment mixture. Also, the performance of anticorrosive paints was evaluated.
Deya, Marta Cecilia +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A MATHEMATICAL MODEL TO DESCRIBE THE SYNERGISTIC EFFECT BETWEEN SULFAMETHOXAZOLE AND TRIMETHOPRIM [PDF]
Journal of Sciences, Islamic Republic of Iran, 1991 b a s e don folic acid biosynthetic pathway a mathematical model was made for bacterial growth to describe the synergistic effect between sulfamethoxazole and trimethoprim.
doaj
Molecules, 2017 Accelerating emergence of antimicrobial resistance among food pathogens and consumers’ increasing demands for preservative-free foods are two contemporary challenging aspects within the food industry.
Shohreh Fahimirad +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
In Vitro Antifungal Activity of Chitosan-Polyphenol Conjugates against Phytophthora cinnamomi
AgriEngineering, 2020 Phytophthora cinnamomi is responsible for radical rot in a wide range of hosts, resulting in large economic and ecological losses worldwide. In Spain, it is responsible for diseases such as the oak decline or the chestnut blight. In this study, different
Petruta Mihaela Matei +6 more
doaj +1 more source