Results 71 to 80 of about 84,785 (254)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Reformation Redivivus: Synergism and the New Perspective

open access: yes, 2009
Debates over the New Perspective on Paul show a great deal of similarity to Reformation-era debates over synergism. In fact, synergism has become one of the more common charges made against the New Perspective by its critics. After documenting the charge
Yinger, Kent L.
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Synergism of microwaves and ultrasound for advanced biorefineries [PDF]

open access: yes, 2015
Conventional energy sources are limited and non-renewable and their consumption contributes to greenhouse gas emissions. The world is in need of advanced biorefineries to meet ever growing energy demands associated with population growth and economic ...
Gude, Veera Gnaneswar   +1 more
core   +1 more source

Insecticidal Synergism with Valone [PDF]

open access: yesNature, 1954
THE insecticidal properties of valone (2-isovaleryl 1,3-indandione) were being investigated some years ago1, when the material was apparently eclipsed by the discovery of DDT. Recent tests on insect pests of stored products have shown that, although not outstandingly insecticidal by modern standards, valone has an unusual combination of properties ...
openaire   +2 more sources

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Peripheral Synergism Between Tramadol and Ibuprofen in the Formalin Test

open access: yes, 2014
peer reviewedAnalgesics with different mechanisms of action can be combined in order to obtain Pharmacological synergism, employing lower doses of each agent, thus diminishing side effects.
Daniel Chavarria‐Bolaños   +7 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides

open access: yes, 2018
Ammar Almaaytah,1 Mohammed T Qaoud,1 Ahmad Abualhaijaa,2 Qosay Al-Balas,3 Karem H Alzoubi4 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Applied Biological ...
Alzoubi KH   +4 more
core  

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