Results 141 to 150 of about 957,593 (356)

Supplementary Figure 1 Legend from Synergistic Effect of Oncogenic <i>RET</i> and Loss of <i>p18</i> on Medullary Thyroid Carcinoma Development [PDF]

open access: gold, 2023
Wendy van Veelen   +6 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

open access: yes, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Mno2 Nanoparticles Supported on Cnts for Cumene Oxidation: Synergistic Effect and Kinetic Modelling

open access: green, 2022
Yuchan Deng   +7 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Emissions cap and structural adjustment11 The authors acknowledge financial support from the Natural Science Foundation of China (No. 72341008, 72341011, 72121002) and Ministry of Education Project of Key Research Institute of Humanities and Social Sciences at Universities in China (No. 22JJD790058, 22JJD790013).

open access: yesChina Economic Quarterly International
We use the strengthening of China's emission target control regime during the Eleventh Five-Year Plan period as a quasi-natural experiment to study the impact of strengthened environmental regulation on firm's emissions and other economic performances ...
Huanhuan Wang, Haichao Fan, Shiyi Chen
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Mutual antimicrobial effect of hibiscus acid and nalidixic acid against multidrug-resistant foodborne bacteria in CD-1 mice

open access: yesJournal of Infection in Developing Countries
Introduction: The antimicrobial effect of hibiscus acid (HA) alone and in combination with nalidixic acid (NA) on multi-antibiotic-resistant Shiga-like toxin-producing Escherichia coli (STEC) and Salmonella Typhimurium (ST) was evaluated in CD-1 mice.
Esmeralda Rangel-Vargas   +6 more
doaj   +1 more source

Evaluation of Synergistic Effect of Heteroaryl-Ethylene Molecules in Combination with Antibiotics: A Preliminary Study on Control Strains

open access: green, 2023
Carmelo Bonomo   +11 more
openalex   +2 more sources

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