Results 81 to 90 of about 9,227,129 (320)

Antimicrobial resistance: a biopsychosocial problem requiring innovative interdisciplinary and imaginative interventions [PDF]

, 2018
To date, antimicrobials have been understood through largely biomedical perspectives. There has been a tendency to focus upon the effectiveness of pharmaceuticals within individual bodies.
Bandura A, Cabinet Office, Department of Health, Department of Health PHE, Department for Environment Food &, Fishbein M, MacPherson D, Michie S, O’Neill J, Paul Flowers   +8 more
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Can market-oriented environmental regulation achieve synergistic reduction of atmospheric pollution and carbon emissions? Evidence from China's carbon emissions trading policy

Cleaner Environmental Systems
Promoting the synergistic reduction of atmospheric pollution and carbon emissions is of great significance for China to achieve its emission reduction commitments.
Yuechao Zhao, Yin Feng, Jun Shen, Yijie He   +3 more
doaj   +1 more source

Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

Oncotarget, 2016
Adrenocortical carcinoma (ACC) is a rare tumor with very poor prognosis and no effective treatment. The aim of this study was to explore a novel therapy co-targeting EGFR and IGF1R in vitro and vivo.The expression of EGFR and IGF1R were evaluated in a series of adrenocortical tumors by immunohistochemistry.
Xu, Lieyu, Qi, Yicheng, Xu, Yunze, Lian, Jianpo, Wang, Xiaojing, Ning, Guang, Wang, Weiqing, Zhu, Yu   +7 more
openaire   +2 more sources

The synergistic impact of ENSO and IOD on Indian summer monsoon rainfall in observations and climate simulations – an information theory perspective

, 2020
. The El Nino–Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) are two well-known temporal oscillations in sea surface temperature (SST), which are both thought to influence the interannual variability of Indian summer monsoon rainfall (ISMR ...
P. Pothapakula, C. Primo, S. Sørland, B. Ahrens   +3 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Advances in catalysts for synergistic elimination of VOCs and NO_x

能源环境保护
VOCs and NO_x are precursors of PM_2.5 and ozone, which can pose a severe threat to both the environment and human health. Catalytic technology is considered a promising multi-pollution treatment for the synergistic elimination of VOCs and NO_x, and is ...
WANG Zhuo, CHU Peiqi , WEI Lu* , LIU Yuxi, DAI Hongxing, DENG Jiguang*   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

SYNERGETIC IMPACT OF RISKS OF INVESTMENT PROJECTS IN POWER GENERATION BY THE TYPES

Ekonomìčnij Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni "Kiïvsʹkij Polìtehnìčnij Institut", 2015
The article focuses on the importance of evaluating the synergistic impact of project risks for different types of power generation companies in the course of qualitative analysis.
Рената Сергіївна Яресько
doaj   +1 more source